Science News 2023 – International Stroke Conference

Stroke Preclinical Assessment Network Design and Interim Analysis
Lauren H. Sansing, MD, MS, FAHA |Yale School of Medicine, New Haven, Connecticut

• SPAN data summary (PPTX)
• SPAN Network website

Program Chair Tudor Jovin, MD, FAHA and Vice Chair Lauren Sansing, MD, MS, FAHA review the top late-breaking science presented during day-one of #ISC23.

Increased Acute Stroke Treatment Rates In Flint, Michigan. Results From Stroke Ready: A Community Engaged Emergency Department And Community Intervention
Lesli Skolarus
Northwestern University, Chicago, Illinois

• Clinical Trials ID: NCT03645590
• STROKE-READY data summary (PPTX)

Tenecteplase Versus Alteplase In Acute Ischaemic Cerebrovascular Events: A Phase 3, A Multi-centre, Open-label, Randomised Controlled, Non-inferiority Trial
Yongjun Wang, Beijing Tiantan Hospital, CMU, Beijing, China

• TRACE-2 published in The Lancet
• TRACE-2 Summary Slide (PPTX)

Mitch Elkind, MD, MS, MPHIL, FAHA, past president of the American Heart Association, and Lee Schwamm, MD, FAHA, chair of the American Stroke Association Advisory Committee, look back at some of the notable milestones in stroke research and stroke care the ASA has achieved on the 25th anniversary of its founding.

Mitch Elkind, MD, MS, MPHIL, FAHA and José Romano, MD remember their colleague Ralph L. Sacco, MD, MS, FAHA, his contributions to stroke science, and his role as a mentor to others in the field.

Program Chair Tudor Jovin, MD, FAHA and Vice Chair Lauren Sansing, MD, MS, FAHA review the top late-breaking science presented during day-two of #ISC23.

Lauren Sansing, MD, MS, FAHA, Francesca Bosetti, PharmD, PhD, Cenk Ayata, MD, PhD, and Raymond Koehler, MD discuss the purpose, evolution, and future potential of the Stroke Preclinical Assessment Network (SPAN), the largest preclinical assessment ever conducted in any disease area.

A Randomized Trial Of Endovascular Thrombectomy Versus Medical Management For Ischemic Stroke With A Large Ischemic Core On Non-contrast CT Or Perfusion Imaging
Amrou Sarraj, MD, FAHA | University Hospitals Neurological Institute, Cleveland, Ohio

• SELECT2 data summary (PPTX)
• Clinical Trials ID NCT03876457
• Published in NEJM: Trial of Endovascular Thrombectomy for Large Ischemic Strokes(link opens in new window)

Tirofiban For Disabling Stroke Without Large Or Medium Vessel Occlusion
Wenjie Zi | Xinqiao Hospital, Chongqing, China

• RESCUE BT 2 data summary (PPTX)
• RESCUE BT 2 published in International Journal of Stroke

A Randomized Trial Of Endovascular Therapy For Acute Ischemic Stroke With A Large Infarct Core
Xiaochuan Huo, MD, PhD| Beijing Tiantan Hospital

• ANGEL-ASPECT data summary (PPTX)
• Clinical Trials ID NCT04551664
• Published in NEJM: Trial of Endovascular Therapy for Acute Ischemic Stroke with Large Infarct
• Editorial in NEJM: Improved Prospects for Thrombectomy in Large Ischemic Stroke