Science News 2023 – International Stroke Conference

Welcome to #ISC23 Science News!

This is where you will find in-depth interviews from investigators and AHA/ASA experts on the Tier 1 late-breaking clinical trials during International Stroke Conference 2023. Expect at-a-glance summaries, analysis, and more!

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#ISC23 Presidential Address: Michelle A Albert, MD, MPH, FACC, FAHA, President of the American Heart Association, delivers the presidential address on the science of health disparities during the opening main event session of #ISC23.

Thursday's Selected Science


Increased Acute Stroke Treatment Rates In Flint, Michigan. Results From Stroke Ready: A Community Engaged Emergency Department And Community Intervention
Lesli Skolarus
Northwestern University, Chicago, Illinois

International Stroke Conference attendees walk past a large heart and torch sign on in the convention center.


Tenecteplase Versus Alteplase In Acute Ischaemic Cerebrovascular Events: A Phase 3, A Multi-centre, Open-label, Randomised Controlled, Non-inferiority Trial
Yongjun Wang, Beijing Tiantan Hospital, CMU, Beijing, China

American Stroke Association's 25th Anniversary

Mitch Elkind, MD, MS, MPHIL, FAHA, past president of the American Heart Association, and Lee Schwamm, MD, FAHA, chair of the American Stroke Association Advisory Committee, look back at some of the notable milestones in stroke research and stroke care the ASA has achieved on the 25th anniversary of its founding.

Remembering Ralph Sacco: Past President of AHA

Mitch Elkind, MD, MS, MPHIL, FAHA and José Romano, MD remember their colleague Ralph L. Sacco, MD, MS, FAHA, his contributions to stroke science, and his role as a mentor to others in the field.

#ISC23 Day Two Highlights

Program Chair Tudor Jovin, MD, FAHA and Vice Chair Lauren Sansing, MD, MS, FAHA review the top late-breaking science presented during day-two of #ISC23.

Presented Thursday and published in Stroke

Friday's Featured Science

The Stroke Preclinical Assessment Network (SPAN) Session

Lauren Sansing, MD, MS, FAHA, Francesca Bosetti, PharmD, PhD, Cenk Ayata, MD, PhD, and Raymond Koehler, MD discuss the purpose, evolution, and future potential of the Stroke Preclinical Assessment Network (SPAN), the largest preclinical assessment ever conducted in any disease area.


A Randomized Trial Of Endovascular Thrombectomy Versus Medical Management For Ischemic Stroke With A Large Ischemic Core On Non-contrast CT Or Perfusion Imaging
Amrou Sarraj, MD, FAHA | University Hospitals Neurological Institute, Cleveland, Ohio


Tirofiban For Disabling Stroke Without Large Or Medium Vessel Occlusion
Wenjie Zi | Xinqiao Hospital, Chongqing, China