Recurrent Pericarditis for Professionals

Recurrent Pericarditis Challenges

Illustration showing difference between normal pericardium and pericarditis

Recurrent pericarditis is a common complication after an initial episode of acute pericarditis, characterized by the recurrence of chest pain and signs of cardiovascular inflammation. Recurrent pericarditis presents major short-term and long-term challenges for clinicians and patients alike.

The impact of recurrent pericarditis often extends beyond cardiac effects, with general uncertainty of each recurrence triggering anxiety, depression, and disruption in overall quality of life.

Pericarditis is inflammation of the fibroelastic pericardial sac.
Acute pericarditis has been observed in ≈0.1% of hospitalized patients and 5% of patients admitted to the emergency department with a diagnosis of noncardiac chest pain.

Videos On Demand

This webinar will explore the features of monogenic autoinflammatory diseases as a paradigm for IL-1 mediated recurrent pericarditis. It will also highlight pericarditis as a feature of systemic autoimmune disease and offer pearls for recognizing and diagnosing these conditions. 

This webinar will review the initial diagnosis and clinical evaluation of pericarditis. It will also address risk stratification and outline therapeutic approaches to initial management and preventing recurrence, and the related practical pharmacology.

This webinar provides key takeaways for initial diagnosis and clinical evaluation strategies in recurrent pericarditis. Advances in understanding the pathophysiology and the newest treatments will be highlighted to improve clinical management and decease complications.


Long Term Complications of Recurrent Pericarditis

Presenters: Janet Kloos, RN, PhD, APRN-CCNS, CCRN; Allen Luis, MD; C. Barton Gillombardo, MD; Brian Hoit, MD

Identifying an underlying cause of the clinical features during history-taking may be beneficial. In developed nations, idiopathic and post cardiac surgery are most frequent causes of constrictive pericarditis. In developing and underdeveloped nations and in immunosuppressed patients, tuberculosis is the major cause. This podcast will review the initial diagnosis, clinical evaluation and treatment of the long-term complications of recurrent pericarditis. Listen Now!

Recurrent Pericarditis in Systemic Autoinflammatory and Autoimmune Disease – Clinical Recognition and Management

Presenters: Tevfik Ismail, MB, BS, PhD, FRCP, FACC, FAHA; Claire Peet, MD; Shreyasee Amin, MD, CM, MPH

While healthcare providers may initiate corticosteroids in patients with recurrent pericarditis, patients with autoimmune rheumatic disease and cardiac involvement should also be managed in collaboration with a rheumatologist particularly. In this podcast, experts explore in more detail the diagnosis and clinical features of monogenic autoinflammatory diseases many of which can present with recurrent pericarditis. In addition, discussion will include the spectrum of autoimmune diseases complicated by pericarditis, how to recognize these clinically, and when to call for help. Listen Now!

Recurrent Pericarditis: The Role of IL-1 Blockade

Presenters: Allen Luis, MD; Anene Ukaigwe, MD; Cyrille K. Cornelio, Pharm.D., BCCP

In 2021, the FDA-approved Rilonacept to treat recurrent pericarditis and reduce the risk of recurrence. In this podcast learn more about the role interleukin-1 (IL-1) plays in the pathophysiology of pericarditis. Listen Now!

Pathophysiology of Recurrent Pericarditis 

Presenters: Paul Cremer, MD; Aisha Siraj, MD, FACC; Antonio Abbate, MD, PhD

Listen to this podcast to better understand the triggers causing recurrent episodes of pericarditis. Experts discuss how to assess those triggers to direct optimal therapy.

Beyond Acute – Recurrent Pericarditis

Presenters: Katherine E. Di Palo, PharmD, FAHA, FHFSA, BCACP, BCGP; Farshad Forouzandeh, MD, PhD, FACC, FSCAI; David Lin, MD

In this podcast, Drs. Forouzandeh, Lin, and Di Palo discuss initial management of recurrent pericarditis. Learn how to distinguish acute pericarditis from recurrent pericarditis. They will also explore diagnostic criteria and initial pharmacotherapy for recurrent pericarditis. Listen now to get more insight on care delivery strategies to improve patient outcomes and decrease associated health care costs due to recurrent pericarditis.

Treatment of Acute Pericarditis

Presenters: Tevfik F Ismail, MB, BS, PhD, FRCP, FACC, FAHA; Antonio Brucato, MD; Robert Barcelona, Pharm.D., BCPS 

In this podcast, Drs. Tevfik Ismail, Antonio Brucato, and Robert Barcelona will focus on the treatment of acute pericarditis and review the relevant clinical pharmacology of the agents used. Learn more on the use of drugs that are off-label for acute pericarditis in the United States and other jurisdictions and some practical tips and tricks and pointers towards pitfalls to avoid when managing this condition.

Complications of Acute Pericarditis

Presenters: Christine L. Jellis, MD PhD FACC FASE; Tim Simpson, MD, Pharm D, and Sadeer Al-Kindi, MD, FACC.

Summary: Learn more in this podcast on the causes, complications and treatments of acute pericarditis and explore how to prevent an initial episode of acute pericarditis from evolving into recurrent pericarditis.


What is Acute Pericarditis: Signs and Signals

Presenters: S. Allen Luis, MD, PhD, FRACP, FACC, FASE; James Lloyd, MD; Janet A. Kloos, RN, PhD, APRN-CCNS, CCRN

Summary: Pericarditis is inflammation of the fibroelastic pericardial sac. Acute pericarditis has been observed in ≈0.1% of hospitalized patients and 5% of patients admitted to the emergency department with a diagnosis of noncardiac chest pain. In this podcast, learn the clinical features of Acute Pericarditis.