Risk-Based Primary Prevention of Heart Failure
Published: April 16, 2025
- This scientific statement introduces a risk-based framework for the primary prevention of heart failure (HF) organized around the "CPR" steps: Calculate risk using the PREVENT equation, Personalize prevention through individual and non-traditional risk factors, and Reclassify risk using biomarkers and imaging for earlier intervention and better outcomes.
- The risk-based framework for the primary prevention of HF integrates current HF prevention guidelines and emphasizes evidence-based strategies such as lifestyle interventions and management of comorbidities using pharmacologic and non-pharmacologic therapies to prevent HF across its stages, from at-risk individuals to pre-HF.
- This statement also highlights the significant burden of HF among marginalized populations, including racial, ethnic, and geographic disparities, and integrates strategies to address social determinants of health as a key component of equitable implementation of HF prevention strategies through multidisciplinary approaches and future research.
Supporting Materials
Recommended Reading
- 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure
- 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease
- Novel Prediction Equations for Absolute Risk Assessment of Total Cardiovascular Disease Incorporating Cardiovascular-Kidney-Metabolic Health
- Role of Biomarkers for the Prevention, Assessment, and Management of Heart Failure
- Cardiovascular-Kidney-Metabolic Health
- Addressing Social Determinants of Health in the Care of Patients With Heart Failure
- Implementation of Prevention Science to Eliminate Health Care Disparities
- Social Determinants of Risk and Outcomes for Cardiovascular Disease
- Life’s Essential 8: Updating and Enhancing the American Heart Association’s Construct of Cardiovascular Health