Recommendations for Management of Clinically Significant Drug-Drug Interactions with Statins and Select Agents used in Patients with Cardiovascular Disease

A review of drug-drug interactions with statins and other selected drugs used in patients with cardiovascular disease

• Statins play an important role in clinical management of those at a high risk for atherosclerotic cardiovascular disease and those with atherosclerotic cardiovascular disease.
• The likelihood of these patients taking multiple medications is high, and the possibility for significant drug-drug interactions (DDI’s) should be considered in patients taking statins.
• This statement helps to inform clinicians, optimize management, and minimize drug-drug interactions.