Nonalcoholic Fatty Liver Disease and Cardiovascular Risk

Published: April 14, 2022

Illustration of a fatty liver and a man having chest pains
  • Nonalcoholic fatty liver disease (NAFLD) is an increasingly common condition that affects more than 25% of adults worldwide.
  • This scientific statement reviews the underlying risk factors and pathophysiology of NAFLD, the associations with atherosclerotic cardiovascular disease (ASCVD), diagnostic and screening strategies, and potential interventions.
  • By increasing awareness of NAFLD, facilitating better access to reliable imaging tools for screening for NAFLD, and the development of proven tools for treatment of NAFLD, the rising tide of non-alcoholic steatohepatitis (NASH) and more advanced hepatic disease can be reversed and adverse ASCVD outcomes prevented.