Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling and Precision Medicine
Published: January 12, 2018
- Induced pluripotent stem cells (iPSCs) offer an unprecedented opportunity to study human physiology and disease at the cellular level, and in the practice of precision medicine.
- This statement: (1) summarizes the state-of-the-science on use of iPSCs for modeling cardiovascular traits and disorders and therapeutic screening; (2) identifies opportunities and challenges in the use of iPSCs for disease modeling and precision medicine; and (3) outlines strategies that support use of iPSCs for biomedical applications.
- The statement is not intended to address the use of stem cells as regenerative therapy, such as transplantation into the body to treat ischemic heart disease or heart failure.
Induced PSCs for CV Disease Modeling and Precision Medicine
Circulation Journal YouTube Channel
New Scientific Statement from the American Heart Association on hPSCs published in Circulation: Genomic and Precision Medicine.
- Commentary: Future Directions in Cardiovascular Disease Modeling by Matthew W. Ellis, BS(1,2) and Yibing Qyang, PhD(1,3,4,5)
- Top Things to Know: Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling and Precision Medicine
- Future Translational Applications from the Contemporary Genomics Era
- Assessing Cardiac Metabolism
- The Expressed Genome in Cardiovascular Diseases and Stroke: Refinement, Diagnosis, and Prediction: A Scientific Statement from the American Heart Association
- Enhancing Literacy in Cardiovascular Genetics: A Scientific Statement from the American Heart Association