Considerations for Cardiovascular Genetic and Genomic Research With Marginalized Racial and Ethnic Groups and Indigenous Peoples
Published: July 26, 2021
- Genetic and genomic research is essential to understanding disease mechanisms and identifying new therapeutic targets, yet barriers to research participation by marginalized racial and ethnic groups and Indigenous populations may increase existing health inequities.
- Identification of race, ethnicity and indigeneity is complex socially and genetically, necessitating separation of social determinants of health such as access to health care and neighborhood, from genetic ancestry, when studying the impact of social and demographic factors on biological pathways.
- Practical steps are outlined for conducting genetic and genomic research with marginalized racial and ethnic groups and indigenous peoples, including building trust, engaging community stakeholders, and commitment to ethical principles.
- Commentary: The Racial and Ethnic Inequity in Genomic Medicine -- A Bridge Too Far by Braxton D. Mitchell, PhD, MPH
- Top Things to Know: Considerations for Cardiovascular Genetic and Genomic Research With Marginalized Racial and Ethnic Groups and Indigenous Peoples
- AHA News: Genetic research should start including racial, ethnic and Indigenous groups
- News Release: New statement provides path to include ethnicity, ancestry, race in genomic research