Cardiorenal Syndrome: Classification, Pathophysiology, Diagnosis, and Treatment Strategies

Published: March 11, 2019

illustration of the kidneys and heart
  • There is an overlap between cardiovascular and kidney disease: hemodynamic interactions of heart and kidney failure, the impact on atherosclerotic disease across both organs, and neurohormonal activation are some of several overlap examples.
  • The term cardiorenal syndrome (CRS) includes a spectrum of disorders involving both the heart and kidneys where acute or chronic dysfunction in one organ may induce acute or chronic dysfunction in the other organ.
  • The Council on the Kidney in Cardiovascular Disease of the American Heart Association initiated work on this comprehensive overview of CRS to highlight developments in this ever-growing field.