Blood Culture–Negative Endocarditis
Published: March 17, 2025
- This scientific statement offers a comprehensive framework for diagnosing and treating blood culture-negative endocarditis, including detailed diagnostic approaches and tailored treatment protocols, ensuring more effective patient management.
- Emphasis is placed on recognizing and managing infections caused by hard-to-culture microorganisms such as Coxiella burnetii and Bartonella species, as well as utilizing advanced imaging for cases with inconclusive echocardiographic results.
- The statement details how new imaging and molecular techniques are transforming the diagnosis of blood culture-negative endocarditis (BCNE), providing clearer guidance for health care professionals in identifying and managing this complex condition.
Video: Blood Culture–Negative Endocarditis
Daniel DeSimone, MD, Larry Baddour, MD and Zerelda Esquer Garrigos, MD announce the publication of a new American Heart Association scientific statement and discuss novel diagnostic tools, updated algorithms, and real-world clinical scenarios to improve Blood Culture–Negative Endocarditis patient outcomes.
Supporting Materials
- Commentary: Blood culture negative endocarditis: dire straits for the Heart Team by Cristiane C Lamas, MD MRCP PhD
- Top Things to Know: Blood Culture–Negative Endocarditis