Prevention

Research Focus:
Multifaceted lifestyle interventions aimed at reducing cardiovascular risk among minority children and adults living in Harlem, New York.

Center Director:
Valentin Fuster, MD, PhD, FAHA

Training Director:
Roger Hajjar, MD, FAHA

Principal Investigators:

• Andrew Kasarskis, PhD
  Applying Cross-generation Genetic and Genomic Information to Improve Cardiovascular Disease Prevention


• Zahi Fayad, PhD, FAHA
  Two Intensive Life Style Intervention Programs in Related Caregivers of Preschool Children


• Valentin Fuster, MD, PhD, FAHA
  Children Heart Research Study Program

Research Focus:
Determine why heart-health measures decline from childhood to middle age and see if the latest techniques can help maintain ideal heart health and reverse declines.

Center Director:
Philip Greenland, MD, FAHA

Training Director:
Mercedes Carnethon, PhD, FAHA

Principal Investigators:

• Lifang Hou, MD, PhD
  Epigenetics of Cardiovascular Health Metrics


• Bonnie Spring, PhD, FAHA
  Behavioral Effects on CVH Metrics and Score


• Norrina Allen, PhD
  Trajectories in Cardiovascular Health (CVH) Metrics and Score From Childhood through Middle-Age

Research Focus:
Heart Failure with preserved ejection fraction (HFpEF) prevention and find new interventions that can help heart failure patients in clinical settings.

Center Director:
Joseph Hill, MD, PhD, FAHA

Training Director:
James de Lemos, MD, FAHA

Principal Investigators:

• Joseph Hill, MD, PhD, FAHA
  Molecular mechanisms in the transition from cardiomyocyte hypertrophy to HFpEF


• Benjamin Levine, MD
  Novel HFpEF Prevention Strategies In High Risk Individuals: High Intensity Exercise Training Plus Omega-3 Fatty Acids


• Jarrett Berry, MD, MS, FAHA
  Association Between Physical Activity and Modifiable Intermediate Heart Failure Phenotypes

Research Focus:
Develop new approaches for preventing high blood pressure and understand how salt causes tissue injury, develop a method to detect and lower excess salt, and determine if a simple treatment in one pill can improve cardiovascular health.

Center Director:
David Harrison, MD, FAHA

Training Director:
Meena Madhur, MD, PhD, FACC

Principal Investigators:

• David Harrison, MD, FAHA
  Effect of Salt on Innate and Adaptive Immune Cells in Hypertension


• Jens Titze, MD
  Lowering Tissue Na+ Stores to Reduce Blood Pressure, Systemic Inflammation, and Metabolic Derangement in Aging Humans


• Thomas Jue-Fuu Wang, MD, FAHA
  Prevention of Hypertension and its Complications in a MedicallyUnderserved Population