Cardiometabolic Health and Type 2 Diabetes Mellitus

January 2020-December 2023
Brigham Health and Womens Hospital

Research Focus:
Strategies to Understand Pathobiology, Predictors & Pharmacotherapy to Reduce Adverse CV Outcomes in T2DM (Super-CVDM)

Co-Center Director:
Mark Feinberg, MD, FAHA
Marc Sabatine, MD, MPH, FAHA

Co-Training Director:
Vanita Aroda, MD
Jessica Fetterman, PhD


Principal Investigators

  • Mark Feinberg, MD, FAHA
    Non-coding RNAs in Ischemic Myocardial Disease and Diabetes: Discovery, Pathobiology, and Therapeutic

  • Marc Sabatine, MD, MPH, FAHA
    Risk Prediction and Personalizing Therapy to Reduce Major Vascular, Heart Failure, and Renal Events in Diabetes

  • Naomi Hamburg, MD, FAHA
    Restoring Vascular and Endothelial Health in Patients with Diabetes

University of Iowa Health Care

Research Focus:
A Heart-Liver-Adipose Axis: The Role of Inter-organ Crosstalk in Cardiometabolic Risk

Center Director:
E. Dale Abel, MD, PhD, FAHA

Training Director:
Kamal Rahmouni, PhD, FAHA

Principal Investigators:

  • Ethan Anderson, PhD
    A Heart-Liver-Adipose Axis: The Role of Inter-organ Crosstalk in Cardiometabolic Risk

  • Saumya Das, MD, PhD
    Adipose-derived Regulators of Inter-organ Communication in T2DM and Cardiometabolic Disease

  • Ravi Shah, MD, FAHA
    Molecular Signatures of Dysfunctional Adiposity and Cardiometabolic Disease in Young Adulthood

NYU Grossman School of Medicine

Research Focus:
Diabetes and Vascular Disease Repair in Women and Men (REPAIR)

Center/Training Director:
Ira Goldberg, MD, FAHA


Principal Investigators:

  • Edward Fisher, MD, MPH, PhD, FAHA
    Mechanisms that Retard Atherosclerosis Regression in Insulin Resistant and Obese Mice

  • Jeffrey Berger, MD, FAHA
    Diabetes and the Platelet Phenotype: Influence of Sex, Cholesterol Lowering, and Cardiovascular Events

  • Chiara Giannarelli, MD, PhD
    Determinants of Pathological Changes in Atherosclerosis in Women and Men with Diabetes

John Hopkins University and Medicine

Research Focus:
Address critical knowledge gaps in the basic biology and effective treatment of pediatric and adolescent obesity.

Co-Center Director:
Chiadi Ndumele, MD, PhD, FAHA
Rexford Ahima, MD, PhD

Training Directors:
Erin Michos, MD, MHS, FAHA


Principal Investigators:

  • Rexford Ahima, MD, PhD Divergent Adipokine Mouse Models and Diabetic Cardiomyopathy

  • Chiadi Ndumele, MD, PhD, FAHA
    Elizabeth Selvin, PhD, FAHA

    Serum Adipokines, Metabolic Risk Progression, and Heart Failure