Cardiometabolic Health and Type 2 Diabetes Mellitus

Research Focus:
Strategies to Understand Pathobiology, Predictors & Pharmacotherapy to Reduce Adverse CV Outcomes in T2DM (Super-CVDM)

Co-Center Director:
Mark Feinberg, MD, FAHA
Marc Sabatine, MD, MPH, FAHA

Co-Training Director:
Vanita Aroda, MD
Jessica Fetterman, PhD

Principal Investigators

• Mark Feinberg, MD, FAHA
  Non-coding RNAs in Ischemic Myocardial Disease and Diabetes: Discovery, Pathobiology, and Therapeutic


• Marc Sabatine, MD, MPH, FAHA
  Risk Prediction and Personalizing Therapy to Reduce Major Vascular, Heart Failure, and Renal Events in Diabetes


• Naomi Hamburg, MD, FAHA
  Restoring Vascular and Endothelial Health in Patients with Diabetes

Research Focus:
A Heart-Liver-Adipose Axis: The Role of Inter-organ Crosstalk in Cardiometabolic Risk

Center Director:
E. Dale Abel, MD, PhD, FAHA

Training Director:
Kamal Rahmouni, PhD, FAHA

Principal Investigators:

• Ethan Anderson, PhD
  A Heart-Liver-Adipose Axis: The Role of Inter-organ Crosstalk in Cardiometabolic Risk


• Saumya Das, MD, PhD
  Adipose-derived Regulators of Inter-organ Communication in T2DM and Cardiometabolic Disease


• Ravi Shah, MD, FAHA
  Molecular Signatures of Dysfunctional Adiposity and Cardiometabolic Disease in Young Adulthood
  
  

Research Focus:
Diabetes and Vascular Disease Repair in Women and Men (REPAIR)

Center/Training Director:
Ira Goldberg, MD, FAHA

Principal Investigators:

• Edward Fisher, MD, MPH, PhD, FAHA
  Mechanisms that Retard Atherosclerosis Regression in Insulin Resistant and Obese Mice


• Jeffrey Berger, MD, FAHA
  Diabetes and the Platelet Phenotype: Influence of Sex, Cholesterol Lowering, and Cardiovascular Events


• Chiara Giannarelli, MD, PhD
  Determinants of Pathological Changes in Atherosclerosis in Women and Men with Diabetes

Research Focus:
Address critical knowledge gaps in the basic biology and effective treatment of pediatric and adolescent obesity.

Co-Center Director:
Chiadi Ndumele, MD, PhD, FAHA
Rexford Ahima, MD, PhD

Training Directors:
Erin Michos, MD, MHS, FAHA

Principal Investigators:

• Rexford Ahima, MD, PhD Divergent Adipokine Mouse Models and Diabetic Cardiomyopathy


• Chiadi Ndumele, MD, PhD, FAHA
  Elizabeth Selvin, PhD, FAHA
  Serum Adipokines, Metabolic Risk Progression, and Heart Failure