Early Innovators Spotlight Sessions

Meet our newest Innovators at #AHA23

The American Heart Association’s Early Innovators Spotlight is a pilot program providing AHA early career grant awardees an opportunity to share their science on a global stage and help them become more involved with the AHA. Predoctoral and Postdoctoral Fellowship awardees will present their science, providing you with a unique chance to learn about their projects and engage in a discussion. Join us in CardioTalk Theater I in the Science and Technology Hall on Saturday and Sunday.

AHA Early Career Innovators

Spotlight 1: Basic Science

AHA Early Innovators Spotlight 1

Saturday, November 11
9:45 a.m. to 11:30 a.m.
CardioTalk Theater I, Science and Technology Hall

Spotlight 1: Basic Science
Time Presentation
9:45 a.m. Defining the Role of Neutral Sphingomyelinases in Regulating Cardioprotective Caveolae and Atrial Myocyte Function
Daniel Turner, University of Wisconsin-Madison
9:56 a.m. RXR to restore cleanup function of microglia/macrophages in aging brain and improve post-stroke recovery
Shun-Ming Ting, UT Health Science Center Houston
10:07 a.m. Going From Outside In? - Epigenetic Regulation of Adventitial Fibroblast’s Role in Atherosclerosis by TCF21
Wenduo Gu, PhD, Stanford University
10:18 a.m. Vascular Signaling Plasticity Reprograms Blood Delivery Mechanisms to Meet Fluctuating Neuronal Energy Needs
Nick Weir, PhD, University of Maryland Baltimore
10:29 a.m. Platelet endocytosis and exocytosis in wound healing and aortic aneurysm
Daniëlle Coenen, PhD, University of Kentucky
10:40 a.m. Using patient specific computational modeling for interventional treatment of mitral regurgitation
Gediminas Gaidulis, Phd, Emory University
10:51 a.m. Understanding T Cell Promiscuity in Autoimmune Disease to Improve Cardiovascular Health
Ruby Sharma, PhD, Albert Einstein College of Medicine
11:02 a.m. The role of Cdkl5 in DNA damage response and acute kidney injury
Josie Silvaroli, The Ohio State University

Spotlight 2: Basic Science

AHA Early Innovators Spotlight 2

Saturday, November 11
11:30 a.m. to 12:57 p.m.
CardioTalk Theater I, Science and Technology Hall

Spotlight 2: Basic Science
Time Presentation
11:30 a.m. Mechanism of Loss of Small Pulmonary Blood Vessels in Cystic Fibrosis
Jean-Pierre Amoakon, University of Cincinnati/Cedars-Sinai Medical Center
11:41 a.m. Mechanism of hypertension in non-alcoholic fatty liver disease
Olufunto Badmus, PhD, University of Mississippi Medical Center
11:52 a.m. The necessary role of ceramide within the human microvascular endothelium
Gopika Senthil Kumar, Medical College of Wisconsin
12:03 p.m. YAP regulates serine biosynthesis and protects heart function during compensatory cardiac hypertrophy
Chengchen Hu, Rutgers, New Jersey Medical School
12:14 p.m. Myosin Binding Protein H-like regulates atrial sarcomere contraction through direct myofilament interactions
Alejandro Alvarez-Arce, PhD, Loyola University Chicago
12:25 p.m. Smad6 in Cardiac Fibrosis
Harikrishnan Venugopal, Albert Einstien College of Medicine
12:36 p.m. Developing Novel Platelet Diagnostic Tools using Force-Triggered CRISPR-Cas12a Assays
Yuxin Duan, PhD, Emory University
12:47 p.m. Developmental and Injury Regulation of Polyploidy in the Drosophila Heart
Archan Chakraborty, PhD, Duke University

Spotlight 3: Basic Science

AHA Early Innovators Spotlight 3

Saturday, November 11
1:15 p.m. to 3:00 p.m.

Spotlight 3: Basic Science
Time Presentation
1:15 p.m. Systematic analysis of MYB-like transcription factors in Toxoplasma
Dominic Schwarz, MIT
1:26 p.m. Acetyl-CoA's role at the intersection of metabolic and epigenetic regulation of innate host defense in the lung
Mikel Haggadone, PhD, University of Pennsylvania Perelman School of Medicine
1:37 p.m. Elucidating the Role of ADAMTS7 in Atherosclerosis
Allen Chung, Columbia University
1:48 p.m. Characterizing the Neuroprotective Effects of Ripk2 Deficiency in Experimental Ischemic Stroke
Jonathan Larochelle, University of Florida
1:59 p.m. RAB5C is a novel regulator of endothelial granule release
Paula Reventun, PhD, Johns Hopkins University School of Medicine
2:10 p.m. Molecular Aspects of Cardiac Arrhythmias in Hypertrophic Cardiomyopathy
Pooneh Nabavizadeh, MD, University of Cincinnati
2:21 p.m. One carbon metabolism defect in heart failure
Jae Woo Jung, PhD, University of
2:32 p.m. A Multiscale Predictive Framework for Thrombus Growth Under Flow
Kaushik Shankar, University of Pennsylvania

Spotlight 4: Clinical & Population Science

AHA Early Innovators Spotlight 4

Saturday, November 11
3:00 p.m. to 4:30 p.m.
CardioTalk Theater I, Science and Technology Hall

Spotlight 4: Clinical & Population Science
Time Presentation
3:00 p.m.. Examining the Associations of Family-related Factors with Hypertension in Sexual Minority Women
Yashika Sharma, RN, Columbia University School of Nursing
3:11 p.m. The Role of Potassium Supplementation on Endothelial Function and Blood Pressure Reactivity on a High Sodium Diet
Andrea Lobene, PhD, RD, University of Delaware
3:22 p.m. Personalized brain temperature predictions for improved outcomes after ischemic stroke
Dongsuk Sung, Emory University
3:33 p.m. Impact of Disease-Associated Variants in Cardiomyopathy Genes in Ethnic Minorities with Early-Onset Atrial Fibrillation
Michael Hill, MD, University of Illinois, Chicago
3:44 p.m. Milk intake and cardiovascular disease: the role of LCT genotype, circulating metabolites, and the gut microbiome
Kai Luo, PhD, Albert Einstein College of Medicine
3:55 p.m. Regulation of ER-mitochondrial Ca2+ transfer by MIRO1 in smooth muscle proliferation and neointima formation
Benney Endoni, University of Iowa
4:06 p.m. Mechanisms limiting stroke volume reserve during exercise in patients with HFpEF
Denis Wakeham, PhD, UT Southwestern Medical School

Spotlight 5: Clinical & Population Science

AHA Early Innovators Spotlight 5

Sunday, November 12
9:45 a.m. to 11:30 a.m.
CardioTalk Theater I, Science and Technology Hall

Spotlight 5: Clinical & Population Science
Time Presentation
9:45 a.m. Identifying mechanisms for low cardiorespiratory fitness with metabolic disease
Rogerio Nogueira soares, PhD, Joslin Diabetes Center/Harvard Medical School
9:56 a.m. The association of neighborhood establishments with post-stroke outcomes in a biethnic population-based cohort
Leanna Delhey, PhD, MPH, University of Michigan
10:07 a.m. Sex Differences in Neuromuscular Fatigability Post Stroke
Zhilun Zhou, Marquette University
10:18 a.m. Genetic causes of thoracic aortic aneurysm and dissection, and modeling heritable risk
John DePaolo, MD, PhD, University of Pennsylvania, Perelman School of Medicine
10:29 a.m. Lipomatous Metaplasia Facilitates Slow Conduction within Ventricular Tachycardia Reentry in Post-Infarct Myocardium
Lingyu Xu, MD, PhD, University of Pennsylvania
10:40 a.m. Glycemic Variability as a Novel Risk Factor for Cardiovascular Disease in Patients with Chronic Kidney Disease
Mengyao Tang, MD, Massachusetts General Hospital
10:51 a.m. Effects Of Statin And Omega-3 Therapies On Bioactive Lipids: An Ancillary Study From Two Randomized Clinical Trials
Rosangela Hoshi, PhD, Brigham and Women's Hospital
11:02 a.m. Role of HDL-Associated Proteoforms in Coronary Artery Disease
Anamika Gangwar, PhD, UT Southwestern Medical Center

Spotlight 6: Basic Science

AHA Early Innovators Spotlight 6

Sunday, November 12
11:30 a.m. to 1:00 p.m.
CardioTalk Theater I, Science and Technology Hall

Spotlight 6: Basic Science
Time Presentation
11:30 a.m. A Novel Role of SMYD2/SOX9 Regulatory Axis in VSMC Osteogenic Differentiation and Atherosclerotic Calcification
Shaligram Sharma, Georgia State University
11:41 a.m. Elucidating the role of fatty acids uptake in thrombopoiesis during diet-induce obesity
Maria Barrachia, PhD, Harvard Medical School/Boston Children's Hospital
11:52 a.m. Hypoxic signaling and endothelial metabolic reprogramming in post-ischemic kidney Injury
Ratnakar Tiwari, PhD, Northwestern University
12:03 p.m. Pathogenic Role of Skeletal Muscle Thioesterase Superfamily Member 2 in Hepatic Steatosis and Insulin Resistance
Yang Xie, PhD, Brigham & Women's Hospital
12:14 p.m. Novel mechanism of neural control of breathing in acute lung injury
Kajal Kamra, University of Nebraska Medical Center
12:25 p.m. Role of the super-relaxed state of ß-cardiac myosin in the pathomechanism of dilated cardiomyopathy
Rama Reddy Goluguri, PhD, Stanford University
12:36 p.m. Tissue Factor Maintenance of Lung Barrier Integrity in ALI through beta-1 Integrin-Mediated Epithelial Cell Adhesion
Brandon Baer, PhD, Vanderbilt University Medical Center
12:47 p.m. A Novel Aptamer-mediated Approach for Treating Heart Failure
Lisa Green, PhD, University of Cincinnati