COVID 19 Content: An AHA Compendium

The American Heart Association is working to ensure optimal care for patients with cardiovascular disease who contract coronavirus (COVID-19). Patients with underlying cardiovascular diseases appear to have an increased risk for adverse outcomes with COVID-19. Here are some helpful resources for health systems, clinics, care providers, patients and the public.

Recently published in AHA journals

Two masked health care professionals care for a patient breathing oxygen on a gurney in a hospital bed.Stroke Acute Management and Outcomes During the COVID-19 Outbreak
Blanca Fuentes, María Alonso de Leciñana, et al.
Stroke, Jan. 7, 2021
A multicenter cohort study to compare stroke outcomes between COVID-19 patients and those without the disease.

Lack of Evidence of ACE2 Expression and Replicative Infection by SARSCoV-2 in Human Endothelial Cells
Ian R. McCracken, Gaye Saginc, et. al.
Circulation, Jan. 6, 2021
This research letter describes a study examining whether SARS-CoV-2 binds directly or indirectly with endothelial cells.

Concerns on the Specificity of Commercial ELISAs for the Measurement of Angiotensin-(1-7) and Angiotensin II in Human Plasma
Mark C. Chappell, et al.
Hypertension, Jan. 5, 2021
A research letter describing comparison of angiotension II (Ang II) and ANG-(1-7) in plasma assessed by a commercial enzyme-linked immunosorbent assay test (ELISA) to that obtained from validated RIAs (radioimmunityassays) in a lab.

Impact of arterial stiffness on all-cause mortality in patients hospitalized with COVID-19 in Spain
Enrique Rodilla, Maria Dolores Lopez-Carmona, et al.
Hypertension, Dec. 30, 2020
This study from Spain looks at the role arterial stiffness may play in COVID-19 mortality.

Analysis of Nationwide Stroke Patient Care in Times of COVID-19 Pandemic in Germany
Daniel Richter, Jens Eyding, Ralph Weber, Dirk Bartig, Armin Grau, Werner Hacke and Christos Krogias
Stroke, Dec. 24, 2020
A look at stroke care and diagnosis in Germany as the pandemic raged. 

Journey to a Receptor for Advanced Glycation End Products Connection in Severe Acute Respiratory Syndrome Coronavirus 2 Infection
Divya Roy, Ravichandran Ramasamy and Ann Marie Schmidt
ATVB, Dec. 17, 2020
The authors explore whether the receptor for advanced glycation end products (RAGE) plays a role in extreme organ damage seen in some SARS-CoV-2 patients.

Stroke and Brain Health

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Learning/CME

HeartBEATS from Lifelong Learning, Science Series: COVID-19 Cardiovascular Syndrome (Paid, credit available)
Listen to a discussion on COVID-19 Syndrome and cardiac damage.

2020 AHA Western States COVID-19 Webinar Series: Strategic Ways To Navigate Stroke Care And COVID-19 (Free, credit available)
Understand the variety of clinical presentations, including cardiomyopathy, ventricular arrhythmias and hemodynamic instability in SARS-CoV-2 infection, and formulate appropriate treatment plans.

COVID-19 Ventilator Reskilling (Paid, certificate available)
This self-directed, adaptive eLearning course helps health care providers in the acute care setting improve knowledge and competence in mechanical ventilation skills.

Patient on Vent

Vulnerable Populations

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AHA's FIT (Fellows-in-Training) bloggers share what they are seeing:

Featured Videos

The Critical Role of Health Care Professionals During the COVID-19 Pandemic

Dr. Stephen Hahn, FDA Commissioner speaks with health care professionals about the FDA’s role in responding to the COVID-19 public health emergency, and the critical role of medical professionals as they face the challenges of COVID-19 response. Transcript of Dr. Hahn's August 10, 2020 remarks

COVID-19 and the Heart

Mina Chung, MD interviews Eduardo Marbán, MD, PhD about his invited lecture on "COVID and the Heart," which he presented Monday during BCVS 2020. Read Dr. Marban's April article in Circulation Research entitled "COVID-19 and the Heart."

COVID-19 and Venous Thromboembolism

Mina Chung, MD interviews Sanjum Sethi, MD, MPH about his BCVS 2020 invited lecture on "COVID-19 and Thromboembolism," which presents some of the lessons he learned from treating COVID-19 patients during the pandemic surge in New York.

Podcasts

Featured Podcast

COVID-19 and Thrombosis

Part of AHA's COVID-19 Clinical Guidance Podcast Series

This 25-minute discussion touches on the unique coagulopathy caused by the SARS-CoV-2 virus, along with diagnosis and thrombo-prophylaxis techniques and treatment options. Featuring Naomi Hamburg, MD, MS, FACC, Associate Professor of Medicine, Boston University; and Mary Cushman, MD, MSc, FAHA, Professor of Medicine, University of Vermont. Read a transcript here (PDF).

 Other Podcasts

Resuscitation and Emergency Guidance

The Implications of COVID19 on Patient Care and Provider Safety

AHA experts and volunteers discuss the real-world implications of the novel coronavirus on patient care and how it affects provider safety, as part of AHA's Get With The Guidelines initiatives. Read a transcript here (PDF).

AHA Research Community

Lawrence Livermore National Labs/AHA COVID-19 Data Portal


This collaboration on the protein atlas developed through the AHA Center for Accelerated Discovery is being leveraged to help accelerate discovery of therapeutic antibodies or antiviral drugs for SARS-CoV-2.

This searchable data portal houses a wealth of data LLNL scientists have gathered from their ongoing COVID-19 molecular design projects, particularly the computer-based "virtual" screening of interactions with SARS-CoV-2 viral proteins for drug design purposes.

Other Resources