The Expressed Genome in Cardiovascular Diseases and Stroke: Refinement, Diagnosis, and Prediction
Published: July 31, 2017
- “Omics” studies promise to deepen our understanding of cardiovascular diseases and stroke and improve our ability to diagnose, predict, and prognosticate diseases in individual patients—a key goal of precision medicine.
- We now have the ability to address disease on levels that were inaccessible to us during the last century: the genome, transcriptome, epigenome, proteome, metabolome, cells, tissues, and organs.
- A critical step towards the widespread use of the expressed genome in the clinic is funding of large-scale efforts to validate, replicate, and integrate the information streams arising from various -omics studies.
Supporting Materials
- Commentary: Looking Beyond DNA Sequence in Studies of Cardiovascular Disease by Chen Yao and Daniel Levy
- Top Things to Know: The Expressed Genome in Cardiovascular Diseases and Stroke: Refinement, Diagnosis, and Prediction
- AHA News: The future of heart disease prevention? How your genome expresses itself