PFO and Stroke
Published: May 11, 2009
AHA/ASA/ACCF Percutaneous Device Closure of Patent Foramen Ovale for Secondary Stroke Prevention: A Call for Completion of Randomized Clinical Trials
- Observational studies suggest a strong association between patent foramen ovale (PFO) and cryptogenic stroke (CS).
- A causal relationship has not been convincingly established for most affected patients.
- Randomized controlled trials offer the best means to help resolve the uncertainty regarding optimal care for patients with CS and PFO.