AMR Of Heart Transplants: Emerging Knowledge

Published: April 02, 2015

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  • Antibody-mediated rejection (AMR) is associated with transplant failure, reduced survival, increased rate of coronary allograft vasculopathy (CAV), and overall poor prognosis.
  • Recent updates to the definition of AMR are expected to reduce variation in the diagnosis of AMR, allowing the development of more standardized therapies.
  • This scientific statement provides an overview of the current diagnosis and treatment of AMR following cardiac transplant and includes recommendations for evolving standardization and future study.