Science News from IKDS 2018

Kawasaki disease (mucocutaneous lymph node syndrome) is a children's illness characterized by fever, rash, swelling of the hands and feet, irritation and redness of the whites of the eyes, swollen lymph glands in the neck, and irritation and inflammation of the mouth, lips and throat.

The heart may be affected in as many as one of five children who develop Kawasaki disease. Damage sometimes occurs to the blood vessels that supply the heart muscle (the coronary arteries) and to the heart muscle itself.

Since the historic first International Kawasaki Disease Symposium in 1984, the international symposium has been held every 3 years in Japan, the United States, or Taiwan, drawing attendees from all continents.

IKDS 2018 Science Highlights

Jane C. Burns, MD, and Jane Newburger, MD, MPH provide a recap of some of the breakthrough basic and clinical science presented during the 12th International Kawasaki Disease Symposium in Yokohama, Japan.

Tomisaku Kawasaki

Tomisaku Kawasaki, MD,at the 2018 International Kawasaki Disease Symposium.

12th International Disease Symposium in Yokohama

(L-R) Jane Newberger, Tomisaku Kawasaki, and Jane Burns, at the 12th International Disease Symposium in Yokohama, Japan.

Interviews with Tomisaku Kawasaki, MD

At the last IKDS meeting in 2015, Tomisaku Kawasaki, MD spoke at length with AHA volunteers about the disease that bears his name. Below are the videos, divided into four topics of interest.

Discovery, Now, and the Future — Part 1 of 4

AHA President Elliott Antman, MD (2015–2016) interviews Jane Newburger, MD, MPH, and Tomisaku Kawasaki, MD about the first Kawasaki Disease patient, who was identified by Dr. Kawasaki in 1969 and is still alive today. In Part 1, Dr. Kawasaki describes the symptoms that led to his identification of the new disease. Ms. Yuri Kitayama provides the Japanese-to-English translation for Dr. Kawasaki.

KD, The Heart, and Stroke — Part 2 of 4

In this video, Dr. Antman interviews Dr. Kawasaki and Dr. Newberger about the pathophysiology of KD, the heart, and stroke. Again, Ms. Yuri Kitayama provides the English translation.

Exploration and Opportunities – Part 3 of 4

In Part 3, Dr. Antman, Dr. Newburger and Dr. Kawasaki discuss future research directions and opportunities in studying KD. Ms. Kitayama provides translation.

Accomplishment and Challenge for the Future – Part 4 of 4

Dr. Antman and Dr. Newburger ask Dr. Kawasaki about his proudest accomplishment, and what is also needed to unravel the mystery of KD. Dr. Kawasaki also has a challenge to present and future researchers.