Science News

AHA Council on Hypertension
AHA Council on Kidney in Cardiovascular Disease
American Society of Hypertension
Joint Scientific Sessions 2017
September 14–17, 2017
Hyatt Regency San Francisco | San Francisco, Calif.

Helpful Links

2017 Hypertension Abstracts: published in Hypertension or as downloadable PDF | Hypertension 2017 ePosters(link opens in new window) (opens in new window)

Hypertension 2017 CME (PDF): The American Heart Association designates this live activity for a maximum of 27.25 AMA PRA Category 1 Credit™

Hypertension 2017 Final Program (PDF) | Hypertension 2017 Program Planner(link opens in new window) (opens in new window)

Selected Science from Thursday, Sept. 14



Welcome to Hypertension Scientific Sessions 2017

John Warner, MD, president of the American Heart Association and Joey Granger, PhD, chair of the Council on Hypertension, discuss the important role the Hypertension 2017 Scientific Sessions plays in improving overall patient care.



Program Highlights

Karen Griffin, MD, chair, Hypertension 2017 Program Committee and Pablo Ortiz, PhD, vice-chair, provide an overview of the science they have planned for this year's scientific sessions in San Francisco.



Keynote Lecturer Robert Carey, MD at Hypertension 2017

Joey Granger, PhD, chair of the Council on Hypertension, interviews Keynote Lecturer Robert M. Carey, MD, about the latest science in adult hypertension.



Brent Egan, MD, on the Global Burden of Hypertension

Joey Granger, PhD, chair of the Council on Hypertension, interviews Brent Egan, MD, about the increasing global burden of hypertension.

Liang Xiao

Sympathetic Innervation Promotes Bone Marrow Homing of Hypertension-specific CD8+ Effector Memory T Cells
Liang Xiao | Vanderbilt University Medical Center, Nashville, TN

  • RESULTS: Sympathetic nerves play a role in hypertension via bone marrow regulation.
     
  • Xiao Abstract

Ctcf is Required for Renin Expression and Maintenance of the Structural Integrity of the Kidney Sympathetic Innervation Promotes Bone Marrow Homing of Hypertension-specific CD8+ Effector Memory T Cells
Maria Florencia Martinez | Department of Pediatrics, Child Health Research Center, University of Virginia, School of Medicine, Charlottesville, VA

 
Frank Spradley

Exaggerated Placental Ischemia-induced Hypertension in Endothelin Receptor Type B (ETB)-deficient Pregnant Rats s Independent of Increased sFlt-1 or ROS Levels
Frank T Spradley, University of Mississippi Medical Center, Jackson, MS

  • RESULTS: Endothelin Receptor Type B (ETB) loss may promote preeclampsia hypertension.
     
  • Spradley Abstract
Other Studies of Interest Published Today

Selected science presented Friday, Sept. 15



Hypertension and Dementia: Philip Gorelick, MD, MPH

Rhian Touyz, MD, PhD, deputy editor of Hypertension, interviews Philip Gorelick, MD, MPH, about his lecture on recent research on hypertension and dementia, which he presented for Hypertension 2017.



2017 Pediatric Hypertension Guidelines

Jan Basile, MD, interviews Joshua Samuelson, MD, MPH, about what's new in the 2017 pediatric hypertension guidelines.


Arthur C Corcoran Memorial Lecturer Tomasz Guzik, MD, PhD

Pablo Ortiz, PhD, program committee vice-chair for Hypertension 2017, interviews Tomasz Guzik, MD, PhD, this year's Arthur C. Corcoran Memorial Lecturer.


Sex Differences in Hypertension

Karen Margolis, MD provides a recap of the science discussed in the session Recent Advances in Hypertension: Women's Health.


Is Hypertension a Bone Marrow Disease?

David Harrison, MD discusses recent findings on the role of bone marrow in hypertension.


Gut Microbiome and the Brain

Elaine Richards, PhD describes recent research on the relationship between hypertension, the gut microbiome, and the brain, which she presented for Mohan Raizada, PhD.

Hypertension Early Career Oral Awards Finalists

Carolyn Still

Clinical Outcomes by Race and Ethnicity in the Systolic Blood Pressure Intervention Trials (SPRINT): A Randomized Control Trial
Carolyn H Still | Case Western Reserve University, FPB School of Nursing, Cleveland, OH

  • RESULTS: Regardless of race/ethnicity, blood pressure treatment offers cardiovascular benefits.
     
  • Still Abstract
Gilad Hamdani

Systolic and Diastolic Ambulatory Blood Pressure Affect Target Organ Damage Differently in Adolescents: The SHIP AHOY Study
Gilad Hamdani | Cincinnati Children's Hospital Medical Center, Cincinnati, OH

  • RESULTS: Adolescents’ ambulatory blood pressure may help evaluate risk for target organ damage.
     
  • Hamdani Abstract
Jie Zhang

Prevention of Glomerular Hyperfiltration by Enhancement of Tubuloglomerular Feedback Response Induces Hypertension and Exacerbates Diabetic Kidney Injury
Jie Zhang | The University of South Florida, Tampa, FL

  • RESULTS: Early science suggests that reduction of glomerular hyperfiltration in diabetes may result in adverse effects on blood pressure and the kidneys.
     
  • Zhang Abstract
Muhammad Oneeb Rehman Mian

TLR4 Antagonism Prevents Early Left Ventricular Hypertrophy and Dysfunction Associated With Neonatal Hyperoxia Exposure Sympathetic Innervation Promotes Bone Marrow Homing of Hypertension-specific CD8+ Effector Memory T Cells
Muhammad Oneeb Rehman Mian | CHU Sainte-Justine, Montreal, QC, Canada

  • RESULTS: Blocking TLR4 signaling may benefit neonates.
     
  • Mian Abstract
Andrew Michael South

Influence of Sex and Obesity on the Effect of Preterm Birth on the Renin-angiotensin System in Adolescents
Andrew Michael South |Wake Forest School of Medicine, Winston Salem, NC

  • RESULTS: Preterm birth mechanisms may program individuals for later cardiovascular risk.
     
  • South Abstract
Katrina M Mirabito Colafella

WINNER Chronic Angiotensin Type 2 Receptor Stimulation Abolishes the Sex-difference in Ang II-induced Hypertension
Katrina M Mirabito Colafella | Monash University, Melbourne, Australia

  • RESULTS: Chronic stimulation of angiotensin type 2 receptor (AT2R) and its impact on hypertension in men versus women.
     
  • Colafella Abstract

More Friday presentations

Ronald G Victor

Deoxycorticosterone-induced Hypertension Caused by Fluconazole
Ronald G Victor | Cedars Sinai Medical Center, Los Angeles, CA

  • RESULTS: Case study suggests that hypertension may be a result of high-dose fluconazole. More study is needed.
     
  • Victor Abstract
Other Studies of Interest Published Today

Selected science presented Saturday, Sept. 16



Gregory Fink, PhD - Irvine Page Alva Bradley Lifetime Achievement Awardee

Joey Granger, PhD, chair of the Council on Hypertension interviews Gregory Fink, PhD, winner of two awards: the Irvine Page and Alva Bradley Lifetime Achievement Award, and the 2017 Council on Hypertension Distinguished Achievement Award. Read about all of the 2017 award winners (PDF).



2017 Donald R Seldin Award Winner Donald Kohan, MD, PhD

Pablo Ortiz, PhD, vice-chair of the Hypertension 2017 program committee, interviews this year's Donald R. Seldin Award lecturer Donald Kohan, MD, PhD about his research on the role of Endothelin in hypertension and kidney disease. Read about all of the 2017 award winners (PDF).



Excellence in Hypertension Research Awardee Allyn R Mark, MD

Joey Granger, PhD, chair of the Council on Hypertension, interviews Allyn R. Mark, MD one of the 2017 Excellence in Hypertension Research Awardees. Read about all of the 2017 award winners (PDF).



Excellence in Hypertension Research Awardee Richard J Roman, PhD

Joey Granger, PhD, chair of the Council on Hypertension, interviews Richard J. Roman, PhD, one of the 2017 Excellence in Hypertension Research Awardees, about his work. Read about all of the 2017 award winners (PDF).



2017 Harriet Dustan Award Lecturer Kate Denton, PhD

Karen Griffin, MD, chair of the program committee for Hypertension 2017, interviews Kate Denton, PhD, this year's Harriet Dustan Award Lecturer.

 

Stability of Ambulatory Blood Pressure Patterns Over Time in Children and Adolescents
Coral D Hanevold, University of Washington School of Medicine, Seattle, WA

  • RESULTS: Unstable ambulatory blood pressure patterns over time were noted in this study of children and adolescents.
     
  • Hanevold Abstract
 

Does Intensive Pulse Pressure control results in lower rates of cardiovascular events? An Analysis of Systolic BP Intervention Trial (SPRINT) database
Quan Tran | Pinnacle Health, Harrisburg, PA

  • RESULTS: Higher pulse pressure may identify increased cardiovascular risk.
     
  • Tran Abstract
Shidan Wang

A Simple Algorithm Identifies Hypertensive Patients Who Benefit From Intensive Blood Pressure Lowering
Shidan Wang | University of Texas Southwestern Medical Center, Dallas, TX

  • RESULTS: Risk model looks for a subset of hypertensive patients likely to benefit from intensive blood pressure lowering.
     
  • Wang Abstract
Other Studies of Interest Published Today

Selected science presented on Sunday, Sept. 17



2017 Lewis K Dahl Memorial Lecturer Satoru Eguchi, MD

Karen Griffin, MD, Program Committee Chair, speaks with Satoro Eguchi, MD, PhD about his lecture on angiotension II signaling in vascular pathophysiology.



SHIP AHOY Study Update

Elaine Urbina, MD reports the latest findings from the SHIP AHOY Study, which looks at the role of hypertension in organ damage in adolescents.