Science News
EPI|LIFESTYLE 2017 Scientific Sessions

Epidemiology and Prevention | Lifestyle and Cardiometabolic Health

March 7 – 10, 2017 | Portland, Oregon

AHA Science News is your source for featured epidemiology, prevention, lifestyle and cardiometabolic health science from the EPI|Lifestyle 2017 Scientific Sessions.

Tuesday | Wednesday | Thursday | Friday

Our 2017 Conference

Welcome to EPI|Lifestyle 2017 in Portland, OR

Steven Houser, PhD, president of the American Heart Association, welcomes attendees at the opening session in Portland, OR.

EPI|Lifestyle 2017 Program Highlights

Program chairs Robert Ross, PhD, FAHA and Wayne Rosamond, PhD, MS, FAHA, discuss some of the top goals of the meeting and explore the themes of this year's conference.


Featured Science from Tue., Mar. 7

Poster Session 1: Aging and Elderly


Obesity Status in Younger Age, 39-year Weight Change and Physical Performance in Older Age: the Chicago Healthy Aging Study (CHAS)
Thanh-Huyen T Vu | Northwestern University, Chicago, IL

RESULTS: Physical performance in older age is impacted by obesity and weight gain when younger.



Three Biological Age Estimates May Capture Distinct Aspects of Aging
Joanne M Murabito | Boston University School of Medicine, Boston, MA

RESULTS: Biological age biomarkers may predict age-related disease risk.

Poster Session 1: Global Health


Association Between Socioeconomic Position and Cardiovascular Disease Risk Factors: The Solan Surveillance Study
Anubha Agarwal | Duke University, Durham, NC

RESULTS: In rural India, better socioeconomic position was associated with more cardiovascular risk factors.

Poster Session 1: Genetics


Analysis Commons: Team Science in a Big-data Environment for Genetic Epidemiology
Joshua C Bis | University of Washington, Seattle, WA

RESULTS: The Analysis Commons system combines genotype and phenotype and multiple tools to analyze whole-genome sequences (WGS) and other multi-omic data.


Featured Science from Wednesday, Mar. 8

The Omics of Physical Activity

Maren Laughlin, PhD and K. Sreekumaran Nair, MD, PhD describe some of the recent science on physical activity presented in the "Omics" session on Thursday at EPI|Lifestyle 2017.

The Metabolomics in Women

Deborah Young, MD interviews Kathryn Rexrode, MD about the science she presented on women and metabolomics. Jump to Dr. Rexrode's abstract and results.

Session 4: Weight Gain Trajectories through Youth with Later Health Outcomes


Body Mass Index Growth Trajectories During Childhood and Adult Obesity Risk
Tao Zhang | Tulane University, New Orleans, LA

RESULTS: The roots of adult obesity begin in early childhood.


Associations of Weight Gain From Early to Middle Adulthood With Major Health Outcomes in Later Life
Yan Zheng | Harvard School of Public Health, Boston, MA

RESULTS: Gaining weight in early to middle adulthood associated with increased risk for death and chronic illnesses, and the likelihood of aging in good health is decreased.


Excess Weight, Cardiovascular Events, and Healthy Longevity: The Lifetime Risk Pooling Project
Sadiya S. Khan | Northwestern University, Chicago, IL

RESULTS: Overweight and obesity are associated with a shorter lifespan and more years of one’s life lived with CVD.

Poster Session: Metabolomics/Proteomics and CVD

Metabolomic Profiles Associated with Total and CVD Mortality in Women
Kathryn M Rexrode | Brigham and Women's Hospital, Boston, MA

RESULTS: Plasma metabolites identified in women were associated with increased risks for cardiovascular mortality.

Metabolomic Profiles Associated With Longevity Women
Raji Balasubramanian | University of Massachusetts, Amherst, MA

RESULTS: Eight metabolites found in women were associated with longevity.


Featured Science from Thursday, Mar. 9

Preserving Ideal CV Health beyond Childhood

Justin Zachariah, MD, Sarah de Ferranti, MD, MPH, Elaine Urbina, MD, MS, and Julia Steinberger, MD, report on the latest science on maintaining the ideal health children generally have at birth into midlife and beyond.

The Stamler Research Award for New Investigators


Validity of Cardiovascular Data From Electronic Data Research Networks: The Multi-Ethnic Study of Atherosclerosis (MESA) and HealthLNK
Faraz S Ahmad | Northwestern University, Chicago, IL

RESULTS: This study compared how data correlated for BMI and BP from electronic clinical data research networks to population-based CVD cohorts. BMI was found to be highly correlated.


Gut Microbiota Related Plasma Metabolites and Risk of Cardiovascular Disease in the PREDIMED Study
Marta Guasch-Ferre | Harvard TH Chan School of Public Health, Boston, MA

RESULTS: In this high-risk population, certain gut microbiota-related metabolites were associated with an increased risk for cardiovascular disease.


Childhood Risk Factor Patterns Predict Adult Type 2 Diabetes Better Than Single Childhood Risk Factor Measures: The International Childhood Cardiovascular Cohort (i3C) Consortium
Tian Hu | University of Minnesota, Minneapolis, MN

RESULTS: Multiple childhood risk factor measures were predictive of adult T2DM and suggest the value of risk factor pattern charts.


The Impact of Excess Body Weight on Cardiovascular Disease Mortality From 1990 to 2015 and Drivers of Change at the State-Level in the United States
Marissa B Reitsma | Institute for Health Metrics and Evaluation, Seattle, WA

RESULTS: The need for state-level interventions are highlighted as actions to reduce the prevalence and burden of high BMI.


Volume and Density of Calcium in the Ascending Thoracic Aorta, When Present, Predict Incident Coronary Heart Disease Beyond Coronary Artery Calcium: the Multi-Ethnic Study of Atherosclerosis
Isac C Thomas | University of California, San Diego, La Jolla, CA

RESULTS: Ascending thoracic aortic calcium volume and density was associated with coronary heart disease and may aid in risk prediction.

WINNERS: The Trudy Bush Fellowship for Cardiovascular Disease Research in Women's Health

Associations of Gluten Intake With Type 2 Diabetes Risk and Weight Gain in Three Large Prospective Cohort Studies of US Men and Women
Geng Zong | Harvard T.H. Chan School of Public Health, Boston, MA

Sex Hormone Levels and Change in Left Ventricular Structure Among Men and Women With Preserved Ejection Fraction The Multi Ethnic Study of Atherosclerosis
Vinita Subramanya | Johns Hopkins School of Medicine, Baltimore, MD

Preterm Delivery and Maternal Cardiovascular Risk Factor Trajectories across the Life Course
Amanda R. Markovitz | Harvard T.H. Chan School of Public Health, Boston, MA


Featured Science from Friday, Mar. 10

Vascular Basis of Cognitive Decline

Alvaro Alonso, MD, MPH, PhD, Thanh-Huyen Vu, MD, PhD, and Andreea Rawlings, MS, discuss some of the science on the relationship between vascular health and cognitive decline that was presented the final day of EPI|Lifestyle 2017.

EPI|Lifestyle 2017: What we learned

The program chair and vice chair for EPI|Lifestyle 2017 provide review some of the highlights of the science presented during the meeting in Portland, OR.


ASPC Debate 2017

Debate question: Is personalized medicine compatible with public health?
Presented by the American Society for Preventive Cardiology

ASPC Debate 2017: PRO

Seth Martin, MD, Johns Hopkins University, argues the PRO position on the ASPC Debate 2017 question: Is precision medicine compatible with public health?

ASPC Debate 2017: CON

Seth Baum, MD, president of the American Society of Preventive Cardiology, presents the CON side of the 2017 ASPC debate question.

Vascular basis for cognitive decline

Orthostatic Hypotension is Associated With 20-year Cognitive Decline and Incident Dementia: the Atherosclerosis Risk in Communities (ARIC) Study
Andreea Rawlings | Johns Hopkins University, Baltimore, MD

RESULTS: Midlife orthostatic hypotension (OH) association with dementia and cognitive over the next 20 years raise questions for future study.

Olfactory Function and Neurocognitive Outcomes in Old Age: the Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS)
Priya Palta | University of North Carolina at Chapel Hill, Chapel Hill, NC

RESULTS: Impaired sense of smell may be a marker of neurodegeneration.


Carotid Artery Stiffness and Decline in Cognitive Function Among Women With, or at Risk for, HIV Infection
Daniel Huck | Montefiore Medical Center/Albert Einstein, Bronx, NY

RESULTS: Less carotid stiffness in these women was associated with slower cognitive decline.

Cardiovascular Health at Young and Middle Ages and Dementia in Older Age - The Chicago Heart Association Detection Project in Industry Study
Thanh-Huyen T Vu | Northwestern University, Chicago, IL

RESULTS: Better cardiovascular health when young was associated with lower dementia risk later in life.