Science News 2023 – International Stroke Conference
ISC Sessions: February 8–10, 2023
Kay Bailey Hutchison Convention Center | Dallas, Texas + Virtual
Welcome to #ISC23 Science News!
Important Links
For Virtual Attendees:
For In-Person Attendees:
For Everyone:
- Published abstracts in Stroke
- AHA Newsroom - news releases from #ISC23
- Continuing Education – how to earn credit for attending #ISC23
Wednesday's Featured Science
SPAN Results
Stroke Preclinical Assessment Network Design and Interim Analysis
Lauren H. Sansing, MD, MS, FAHA |Yale School of Medicine, New Haven, Connecticut
#ISC23 Day One Highlights
Program Chair Tudor Jovin, MD, FAHA and Vice Chair Lauren Sansing, MD, MS, FAHA review the top late-breaking science presented during day-one of #ISC23.
More science from Wednesday
AHA Scientific Statement: Ideal Foundational Requirements for Stroke Program Development and Growth
Thursday's Selected Science
STROKE-READY
Increased Acute Stroke Treatment Rates In Flint, Michigan. Results From Stroke Ready: A Community Engaged Emergency Department And Community Intervention
Lesli Skolarus
Northwestern University, Chicago, Illinois

TRACE-2
Tenecteplase Versus Alteplase In Acute Ischaemic Cerebrovascular Events: A Phase 3, A Multi-centre, Open-label, Randomised Controlled, Non-inferiority Trial
Yongjun Wang, Beijing Tiantan Hospital, CMU, Beijing, China
American Stroke Association's 25th Anniversary
Mitch Elkind, MD, MS, MPHIL, FAHA, past president of the American Heart Association, and Lee Schwamm, MD, FAHA, chair of the American Stroke Association Advisory Committee, look back at some of the notable milestones in stroke research and stroke care the ASA has achieved on the 25th anniversary of its founding.
Remembering Ralph Sacco: Past President of AHA
Mitch Elkind, MD, MS, MPHIL, FAHA and José Romano, MD remember their colleague Ralph L. Sacco, MD, MS, FAHA, his contributions to stroke science, and his role as a mentor to others in the field.
#ISC23 Day Two Highlights
Program Chair Tudor Jovin, MD, FAHA and Vice Chair Lauren Sansing, MD, MS, FAHA review the top late-breaking science presented during day-two of #ISC23.
Presented Thursday and published in Stroke
Rapid Activation of Neuroinflammation in Stroke: Plasma and Extracellular Vesicles Obtained on a Mobile Stroke Unit
Robert Kowalski et al.
Endovascular Therapy or Medical Management Alone for Isolated Posterior Cerebral Artery Occlusion: A Multicenter Study
Pierre Seners, Candice Sabben et al.
Tenecteplase Treatment and Thrombus Characteristics Associated With Early Reperfusion: An EXTEND-IA TNK Trials Analysis
Vignan Yogendrakumar et al.
Smoking-Cessation Pharmacotherapy After Stroke and Transient Ischemic Attack: A Get With The Guidelines-Stroke Analysis
Neal S Parikh et al.
Associations Between Long-Term Air Pollutant Exposure and 30-Day All-Cause Hospital Readmissions in US Stroke Patients
Judith H Lichtman, Phoebe Tran et al.
Friday's Featured Science
The Stroke Preclinical Assessment Network (SPAN) Session
Lauren Sansing, MD, MS, FAHA, Francesca Bosetti, PharmD, PhD, Cenk Ayata, MD, PhD, and Raymond Koehler, MD discuss the purpose, evolution, and future potential of the Stroke Preclinical Assessment Network (SPAN), the largest preclinical assessment ever conducted in any disease area.
SELECT2
A Randomized Trial Of Endovascular Thrombectomy Versus Medical Management For Ischemic Stroke With A Large Ischemic Core On Non-contrast CT Or Perfusion Imaging
Amrou Sarraj, MD, FAHA | University Hospitals Neurological Institute, Cleveland, Ohio
RESCUE BT 2
Tirofiban For Disabling Stroke Without Large Or Medium Vessel Occlusion
Wenjie Zi | Xinqiao Hospital, Chongqing, China
ANGEL-ASPECT
A Randomized Trial Of Endovascular Therapy For Acute Ischemic Stroke With A Large Infarct Core
Xiaochuan Huo, MD, PhD| Beijing Tiantan Hospital