2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes
Published: February 27, 2025
- The scope of this guideline is to incorporate new evidence since the publication of the 2013 STEMI and 2014 NSTEMI guideline, and the 2015 Focused Update on Primary PCI in STEMI.
- This new guideline combines these topics into a document that builds upon previously published recommendations and provides new recommendations based on a comprehensive review and synthesis of new evidence.
- This guideline focuses on the acute management of ACS, including unstable angina, NSTEMI, and STEMI.
Video: 2025 Guideline for the Management of Patients With Acute Coronary Syndromes
Authors Sunil Rao, MD, Michelle L. O'Donoghue, MD, MPH, FAHA, and Marc Ruel, MD, MPH, FAHA announce the publication of the new guideline and discuss some of the new evidence that lead to this update.
Supporting Materials
Slide Sets
- AHA Clinical Update: 2025 Guideline for the Management of Patients with Acute Coronary Syndromes
Download AHA Clinical Update Slide Set (PPTX) - Acute Coronary Syndromes Collaborator Infographic
Download the Acute Coronary Syndromes Collaborator Infographic (PDF)
Related Resources
- News Release: ACC/AHA Issue New Acute Coronary Syndromes Guideline
- Home-Based Cardiac Rehabilitation
- Contemporary Diagnosis and Management of Patients With Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease
- Invasive Management of Acute Myocardial Infarction Complicated by Cardiogenic Shock
- Mechanical Complications of Acute Myocardial Infarction
- Systems of Care for ST-Segment–Elevation Myocardial Infarction
- An Update on Radial Artery Access and Best Practices for Transradial Coronary Angiography and Intervention in Acute Coronary Syndrome
- Management of Patients at Risk for and With Left Ventricular Thrombus
- 2021 Guideline for Coronary Artery Revascularization
- 2021 Guideline for the Evaluation and Diagnosis of Chest Pain
- 2022 Guideline for the Management of Heart Failure
- 2023 Guideline for the Management of Patients With Chronic Coronary Disease
- 2018 Guideline on the Management of Blood Cholesterol
- Pocket Guide: Management of Patients With Acute Coronary Syndromes