Fifth Universal Definition of Myocardial Infarction (2026)
Updated: August 28, 2026
- The Fifth Universal Definition of Myocardial Infarction (UDMI) is a joint statement from the European Society of Cardiology (ESC), the American College of Cardiology (ACC), the American Heart Association (AHA), and the World Heart Federation (WHF) and builds on the success of prior consensus statements, which have improved the standardization of the diagnosis of myocardial infarction worldwide.
- The Fifth UDMI updates the classification to better reflect un¬derlying pathophysiology, align with clinical evaluation of patients, and incorporate objective diagnostic criteria.
- This important international scien¬tific effort will continue to require regular revision as new evidence emerges.
Supporting Materials
Recommended Reading
- 2025 Guideline for the Management of Patients With Acute Coronary Syndromes
- 2023 Guideline for the Management of Patients With Chronic Coronary Disease
- Fourth Universal Definition of Myocardial Infarction (2018)
- 2021 Guideline for the Evaluation and Diagnosis of Chest Pain
- Contemporary Diagnosis and Management of Patients With Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease
- 2024 Guideline for Perioperative Cardiovascular Management for Noncardiac Surgery
- Spontaneous Coronary Artery Dissection Current State of the Science