State of the Art: Evaluation and Medical Management of Angina with NonObstructive Coronary Artery Disease

Published: November 10, 2025

Nonobstructive CAD chart showing stages
  • Non-obstructive coronary artery disease (NOCA) is common, carries significant cardiovascular risk, and requires accurate detection and proactive management to improve outcomes.
  • Individualized treatment strategies and intensive risk factor modification—including lipid-lowering and antihypertensive therapies—are essential for patients with NOCA.
  • Ongoing follow-up, recognition in guidelines, and emerging therapies are shaping the evolving care pathway for NOCA patients.