Large-Core Ischemic Stroke Endovascular Treatment
Published: December 17, 2024
- This Science Advisory summarizes recent randomized trials on the efficacy of endovascular thrombectomy (EVT) in large-core ischemic stroke (LCIS), analyze the similarities and differences among these trials, and discuss the clinical implications of their findings.
- The results from six clinical trials examining the efficacy of EVT provide strong evidence of its benefit in patients who have good pre-stroke functional status and significant stroke severity with a LCIS on initial imaging.
- The results reframe current evidence regarding the role of reperfusion therapies in those with larger areas of presumed irreversible ischemia.
Video: Large-Core Ischemic Stroke Endovascular Treatment
Nestor Gonzalez, MD, MSCR, FAANS, FAHA discusses the recent American Heart Association scientific advisory, which highlights the pivotal changes over the last few years in applying endovascular techniques, analyzing six key clinical trials, and the resulting benefits in functional independence and mortality reduction.
Supporting Materials
- Commentary: Maximizing the Benefit of Endovascular Therapy in “Large Core” Strokes. by Joseph P. Broderick, M.D.
- Top Things to Know: Large-Core Ischemic Stroke Endovascular Treatment
Recommended Reading
- Endovascular Treatment and Thrombolysis for Acute Ischemic Stroke in Patients With Premorbid Disability or Dementia
- Care of the Patient With Acute Ischemic Stroke: Update to 2009 Comprehensive Nursing Care Scientific Statement
- Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke