Gene Therapy in Cardiovascular Disease
Published: November 11, 2024
- Many cardiovascular diseases, the leading cause of morbidity and mortality worldwide, are caused by damaging DNA variants and require lifelong treatments that mitigate but do not cure disease.
- Gene therapies deliver exogenous genes to supplement insufficient protein levels or use gene editors to correct, delete, or modify sequences that cause monogenic disorders.
- Educating clinicians, patients, and society is critical to understanding genetic concepts, appropriately interpreting genetic test results, and advancing gene therapies to benefit patients and reduce the burden of cardiovascular disease.
Supporting Materials
Recommended Reading
- Genetic Testing for Inherited Cardiovascular Diseases
- Genetic Testing for Heritable Cardiovascular Diseases in Pediatric Patients
- Considerations for Cardiovascular Genetic and Genomic Research With Marginalized Racial and Ethnic Groups and Indigenous Peoples
- Genetic Basis for Congenital Heart Disease: Revisited
- 2024 Guideline for the Management of Hypertrophic Cardiomyopathy