Precision Medicine

Generation of Human Cardiomyocytes With Adult-Like Metabolism by a Chemically Defined Medium for Mitochondrial Disease Modeling Researchers at Heart Genetic-Phenotypic Discordance Reveals Distinct Cardiovascular and Mortality Risk at HDL Cholesterol Extremes It Takes a Cell Village to Map Individual Cardiotoxicity Risk Cross-Ancestry Portability of a Hypertrophic Cardiomyopathy Polygenic Score in a Diverse US Cohort Investigating the Distinctive Clinical and Genetic Landscape of PPA2 Deficiency F2R Polymorphisms and Efficacy of Clopidogrel Initiated Within 72 Hours for Ischemic Stroke Putting the Brakes on Nuclear Rupture–Driven Remodeling in LMNA Cardiomyopathy Multimodal KCNQ1 Variant-Effect Maps Define Ion Channel Mechanisms and Disease Risk Cardiovascular Genetic Counseling Is Associated With Improved Patient-Reported Outcomes Across Clinical Indications and Settings