Science News for ACC.21

The American Heart Association's Science News from ACC.21 coverage brings you results and insights into selected important scientific trials presented at ACC.21, a virtual conference held May 15-17, 2021. Find at-a-glance data summaries, exclusive interviews, simultaneous publications, and more – all in one place.

Jump to one day's coverage: Saturday  |  Sunday  |  Monday

Quick Reference:
AHA Journals Simultaneous Publications

Saturday's Selected Science


Prospective Arni Versus Ace Inhibitor Trial To Determine Superiority In Reducing Heart Failure Events After Myocardial Infarction
Marc A. Pfeffer, MD, PhD | Distinguished Dzau Professor of Medicine, Harvard Medical School, Brigham and Women’s Hospital, Boston, MA


Investigator Marc Pfeffer, MD, PHD summarizes the results of PARADISE-MI.


Aspirin Dosing: A Patient-centric Trial Assessing Benefits And Long-term Effectiveness Trial
Schuyler Jones, MD | Duke University Medical Center, Durham, NC

ADAPTABLE Study Results

Erin Michos, MD, MHS, FAHA interviews Schuyler Jones, MD about the results of ADAPTABLE.

Sunday's Selected Science


Effects Of Dapagliflozin On Prevention Of Major Clinical Events And Recovery In Patients With Respiratory Failure Due To COVID-19 - Main Results From The DARE-19 Randomized Trial
Mikhail Kosiborod, MD | Saint Luke's Mid America Heart Institute, Kansas City, MO

DARE-19 Results

Sandeep Das, MD interviews investigator Mikhail Kosiborod, MD about the results of DARE-19.

Monday's Selected Science


Care Optimization Through Patient And Hospital Engagement Clinical Trial For Heart Failure: Primary Results Of The Connect-hf Randomized Clinical Trial
Adam D. DeVore, MD, MHS | Duke Clinical Research Institute, Durham, NC


Larry Allen, MD, MHS interviews investigator Adam DeVore, MD, MHS about the results of CONNECT-HF.

HOLIDAY Monitors Study

Acute Alcohol Consumption And Discrete Atrial Fibrillation Events
Gregory M Marcus, MD, MAS | University of California, San Francisco, San Francisco, CA

HOLIDAY Monitors Study Results

Sana M. Al-Khatib, MD, MHS interviews Gregory Marcus, MD, MAS about the results of the HOLIDAY Monitors Study.

Other Late Breaking Science & Simultaneous Publications from ACC.21

Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy (PRADA) Extended Follow-Up of a 2×2 Factorial, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of Candesartan and Metoprolol
Siri Lagethon Heck, et al. | Circulation | May 16, 2021

Late Outcomes of the RAPID-TnT Randomized Controlled Trial: 0/1-Hour High-Sensitivity Troponin T Protocol in Suspected ACS
Kristina Lambrakis, et al. | Circulation | May 16, 2021

Effects of Sacubitril/Valsartan on Serum Lipids in Heart Failure with Preserved Ejection Fraction
Senthil Selvaraj, et al. | JAHA | May 16, 2021

Contemporary National Patterns of Eligibility and Utilization of Novel Cardioprotective Anti‐hyperglycemic agents in Type 2 Diabetes
Arash A Nargesi, et al. | JAHA | May 15, 2021

Temporal Trends, Clinical Characteristics and Outcomes of Emergent Coronary Artery Bypass Grafting for Acute Myocardial Infarction in the United States
Sri Harsha Patlolla, et al. | JAHA | May 15, 2021

Association of Health Insurance Payer Type and Outcomes After Durable Left Ventricular Assist Device Implantation: An Analysis of the STS-INTERMACS Registry
Sameed Ahmed M, et al. | Circulation: Heart Failure | May 15, 2021

Association Between Angiotensin Receptor-Neprilysin Inhibition, Cardiovascular Biomarkers, and Cardiac Remodeling in Heart Failure with Reduced Ejection Fraction
Sean P. Murphy, et al. | Circulation: Heart Failure | May 15, 2021

Social Determinants of Adherence to COVID-19 Risk Mitigation Measures Among Adults with Cardiovascular Disease
Kobina K., et al. | Circulation: Cardiovascular Quality and Outcomes | May 6, 2021

Hospital Variation in 30‐Day Readmissions Following Transcatheter Aortic Valve Replacement
Dhaval Kolte., et al. | JAHA | May 3, 2021