2025 Genomic and Precision Medicine and Epidemiology Mid-Career Research Award and Lecturer – Pradeep Natarajan, MD, MMSc, FAHA

Pradeep Natarajan, MD, MMSc, FAHA

Massachusetts General Hospital/Harvard Medical School
Boston, Massachusetts
Plano, Texas

Dr. Pradeep Natarajan is the Director of Preventive Cardiology and the Paul and Phyllis Fireman Endowed Chair in Vascular Medicine at Mass General Hospital, Associate Director of Personalized Medicine at Mass General Brigham, Associate Professor of Medicine at Harvard Medical School, Associate Professor of Epidemiology at Harvard T.H. Chan School of Public Health, and Associate Member of the Broad Institute of Harvard and MIT. He received his BA in molecular biology from the University of California, Berkeley, and MD from UCSF. He completed his internship and residency in internal medicine at the Brigham and Women’s Hospital, and subsequent cardiology fellowship at the Mass General Hospital.

His research lab spans the MGH Cardiovascular Research Center, MGH Center for Genomic Medicine and Broad Institute's Cardiovascular Disease Initiative. He uses germline and somatic genetic variation to uncover new biology and help enhance clinical care for cardiovascular disease. His scientific contributions include “human knockout” discovery and investigation to prioritize therapeutic targets, elucidating the genetic architecture of cardiovascular diseases and risk factors, construction through implementation of polygenic risk scores for preventive cardiology, and the novel concept of somatic mutations contributing to cardiovascular disease.

He has received several awards, including the 2023 Joseph A. Vita Award from the American Heart Association, as well as mentoring awards from MGH and Harvard Medical School.

In tandem with his research efforts, Dr. Natarajan oversees clinical and training programs on the prevention of cardiometabolic diseases, leading the Mass General Hospital Cardiovascular Disease Prevention Center.