Science News from ACC24

Top Trials from ACC24

Amit Khera, MD, MSc, FAHA and Joanna Chikwe, MD, FAHA, chairs of the American Heart Association Committee on Scientific Sessions Program, comment on the results of some of the top trials presented during ACC 2024.

RELIEVE-HF Commentary
A Double-blind, Randomized Placebo Procedure-controlled Trial of an Interatrial Shunt in Patients With HFrEF and HFpEF: Principal Results From the RELIEVE-HF Trial

VIDEO: RELIEVE-HF Results with Gregg Stone, MD(link opens in new window)

Nancy Sweitzer, MD, PhD, Editor-in-Chief of Circulation: Heart Failure, comments on the results of the RELIEVE-HF trial looking at the safety and efficacy of the V-Wave Ventura IAS device in symptomatic heart failure patients with any left ventricular ejection fraction (LVEF).

Empagliflozin After Acute Myocardial Infarction: Results of the EMPACT-MI Trial

Javed Butler, Stefan D. Anker, Deepak Bhatt, Josephine Harrington, Schuyler Jones, Mark Petrie, Mikhail Sumin, Jacob A. Udell, Isabella Zwiener, Adrian F. Hernandez, Baylor Scott and White Research Institute, Dallas, TX, USA, Boehringer Ingelheim, Ingelheim, Germany

A thumbnail image of the EMPACT-MI data summary

Effect of Gamification, Financial Incentives or Both Combined to Increase Physical Activity Among Patients With Elevated Risk For Major Adverse Cardiovascular Events. The Be Active Randomized Clinical Trial

Gerald Jerome, PhD interviews investigator Alexander Fanaroff, MD about the results of BE ACTIVE, which he presented during ACC.24.

Long-term Beta-blocker Treatment After Acute Myocardial Infarction and Preserved Left Ventricular Ejection Fraction: The REDUCE-AMI Trial

Troels Yndigegn, Bertil Lindahl, Katarina Mars, Joakim Alfredsson, jocelyne benatar, Lisa Brandin, David Erlinge, Claes Held, Patrik Hjalmarsson, Pelle Johansson, Patric Karlström, Thomas W. Kellerth, Toomas Marandi, Annica Ravn-Fischer, Johan Sundstrom, Ollie Östlund, Robin Hofmann, Tomas Jernberg, Karolinska Institutet, Stockholm, Sweden, Lund University, Lund, Sweden
A thumbnail image of a data summary slide

One-month Ticagrelor Monotherapy After PCI in Acute Coronary Syndromes: Principal Results From the Double-blind, Placebo-controlled Ultimate DAPT Trial

Gregg Stone, MD summarizes the results of ULTIMATE DAPT which he presented during ACC.24.

Transcatheter Aortic Valve Implantation (TAVI) Versus Surgical Aortic Valve Replacement (SAVR) in Patients at Low to Intermediate Risk: One Year Outcomes of the Randomized DEDICATE-DZHK6 Trial

Moritz Seiffert, DEDICATE-DZHK6 Study Investigators, German Centrefor Cardiovascular Research (DZHK), University Heart and Vascular Center Hamburg, Hamburg, Germany, German Centre for Cardiovascular Research (DZHK), Germany
A thumbnail image of a summary slide.

Also Published in AHA Journals

Research Article
Qualitative Analysis of Patient Decisional Needs for Medications to Treat Heart Failure
Turgeon et al.
Circulation: Heart Failure, April 6, 2024

GDMT Optimization, But Make It Patient-Centered: Understanding Patient Needs During Heart Failure Medication Discussions
Jocelyn S. Thompson
Circulation: Heart Failure, April 6, 2024

Research article
Early Serial Assessment of Aggregate Vasoactive Support and Mortality in Cardiogenic Shock: Insights from the Critical Care Cardiology Trials Network Registry
Patel et al.
Circulation: Heart Failure, April 8, 2024

Impact of Bempedoic Acid on Cardiovascular Outcomes by Sex
Cho et al.
Circulation, April 6, 2024

Research Article
Clinical Impact of Routine Assessment of Patient-Reported Health Status in Heart Failure Clinic
Sandhu et al.
Circulation, April 7, 2024

Research Article
Visual Estimates of Coronary Slow Flow Are Not Associated with Invasive Wire-Based Diagnoses of Coronary Microvascular Dysfunction
Harkin et al.
Circulation: Cardiovascular Interventions, April 7, 2024

Research Article
Trends and Disparities in Valvular Heart Disease Mortality in the United States From 1999 to 2020
Tan et al.
Journal of the American Heart Association, April 8, 2024