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The Bugher Foundation

American Heart Association & American Stroke Association LogoBugher Foundation Logo

Frederick McLean Bugher established the Henrietta B. and Frederick H. Bugher Foundation in 1961 in honor of his parents.  Both of Mr. Bugher's parents suffered from heart ailments. The foundation continues to support research in cardiovascular and cerebrovascular diseases. Originally limited to research within the District of Columbia, the foundation now supports research throughout the world.

The Bugher Foundation has been partnering with the American Heart Association since 1984 to fund research.  The year 2009 is the 25th anniversary of the collaboration between the two groups.  Click the links below to learn more about the Bugher Foundation and to see a list of current and past AHA/Bugher Foundation awardees.

American Stroke Association-Bugher Foundation Centers for Excellence in Stroke Collaborative Research for Regeneration, Resilience and Secondary Prevention – 2014

In 2011, the Bugher Foundation committed $9.24 million to create a new network of three centers for excellence in stroke collaborative research for a period of four years. This new initiative will support the collaboration of basic, clinical and population researchers from different specialties, whose collective efforts will lead to new approaches to prevent and treat stroke. Efforts will expand upon previous Bugher initiatives by inviting research on recovery after a stroke, including the areas of repair, regeneration, neuroplasticity and rehabilitation. These Centers activate on April 1, 2014. The centers are located at the following institutions:
  • University of California, Los Angeles
  • University of Colorado, Denver
  • University of Miami

American Stroke Association-Bugher Foundation Centers for Stroke Prevention Research - 2007

In 2006 the Bugher Foundation joined with the American Stroke Association, a division of the American Heart Association, to support a network of three Centers for Stroke Prevention Research for four years.  The initiative produced a network of interacting institutions and scientists for collaborative, multidisciplinary research and training to improve the prevention of stroke.  The goals of the initiative were: 

  • Generating innovative ideas
  • Creating dramatic gains in the field
  • Networking to fill knowledge gaps and expertise in research

These awards were activated July 1, 2007 and were funded through June 30, 2011, with a total commitment of $8.4 million.

AHA-Bugher Awards for the Investigation of Stroke - 1998

In 1998, the Bugher Foundation committed $7.5 million over the next eight years to support AHA-Bugher Foundation Awards for the Investigation of Stroke.  In 1999, the Bugher Foundation increased its commitment to this AHA-Bugher initiative by offering the American Heart Association a challenge grant of $1 million to match two for one with new dollars in the community.  The additional contribution from the Bugher Foundation and the community at large supported eight more stroke grants.  The AHA-Bugher Foundation Awards for the Investigation of Stroke encourage development of better stroke preventive measures and better stroke interventions.  The association activated a total of 35 awards in January 2000, January 2001 and July 2005.  This commitment enabled the association to support another of its goals: to expand research funded through the National Center to promising new areas by launching targeted research programs, focusing on any aspect of brain vascular function related to stroke. Such investigations included but were not limited to:

  • Blood brain barrier function
  • Endothelial mechanisms in cerebral vessels
  • Interaction of stroke risk factors with cerebral blood vessels
  • Male/female differences in cerebral blood vessel function
  • Mechanisms of ischemic injury (involving cerebral blood vessels)
  • Molecular biology of cerebral vessels
  • Molecular genetics (of disorders of cerebral blood vessels)
  • Regulation of cerebral blood vessels

Centers for Molecular Biology in the Cardiovascular System - 1984

In 1984 the foundation sought the guidance of the American Heart Association in identifying a focus for its research support. The association suggested a program to bring molecular biology training to clinically-trained investigators. This was the beginning of a continuing relationship with the association.

As a result of a partnership between the Bugher Foundation and the American Heart Association, the Centers for Molecular Biology in the Cardiovascular System was established.  The association administered six Centers for Molecular Biology in the Cardiovascular System from 1986-96, using a $9.4 million contribution from the Bugher Foundation.  About 120 clinically-trained fellows learned molecular biology techniques through the efforts of these six centers. The centers were located at the following institutions:

  • Baylor College of Medicine, Houston
  • Brigham and Women's Hospital
  • Children's Hospital, Boston
  • Stanford University
  • University of California, San Diego
  • University of Texas Southwestern Medical Center at Dallas

Bugher Foundation Current and Past Award Recipients