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ATVB Journal Header Centered 750x266

ATVB Featured Articles
JULY 2020

ATVB_cover_July 2020_150 px
 
About the Cover

Cardiac lymphatics (green, LYVE1) intertwined with arterial tree (red, alphaSMA) of an adult healthy C57Bl/6J mouse heart using lightsheet imaging (courtesy of D. Godefroy, DC2N, Mont-Saint Aignan, France). (See pages 1722–1737.)
 


 Announcement from our Editor-in-Chief, Dr. Alan Daugherty

ATVB is pleased to announce that we are now considering Research Letters for publication. Please visit https://www.ahajournals.org/atvb/article-types for additional information. 
Editor's Pick

Editor's Pick

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Twitter Logo white 30x30Circulating virions (i.e., HIV-1) activate platelets as they are endocytosed, trafficked through platelet endosomal compartments and recognized by Toll-like Receptors to initiate a-granule secretion. @SWWhiteheart

Platelets Endocytose Viral Particles and Are Activated via TLR (Toll-Like Receptor) Signaling
M Banerjee, Y Huang, S Joshi, GJ Popa, MD Mendenhall, QJ Wang, BA Garvy, T Myint, SW Whiteheart

Editor's Note:

This article reports that platelets take up and can be activated by viruses, as demonstrated with both in vitro systems and multiple animal models. It provides mechanistic insights into understanding how platelets function as immune cells in circulation. 
Related Editorial:

Platelets and Immunity: Going Viral
M Koupenova, J Freedman

Featured Articles

ATVB_cover_July 2020_Fig 02 png
 Twitter Logo white 30x30Decreased CD73/adenosine signaling drives FOXO1-induced #vascularcalcification in the #raredisease ACDC and this signaling axis is operative in calcified #PAD vessels
@sthilairelab | @pittvmi | @PittDeptofMed


ATVB_cover_July 2020_Fig 03 png
Twitter Logo white 30x30A feedforward loop between the collagen receptor DDR1 and RhoA drives matrix stiffness-induced vascular calcification and contributes to the initiation and propagation of the pathology. @BendeckBendeck 

 

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