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ATVB Journal Header Centered 750x266

ATVB Featured Articles
May 2020

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About the Cover

GFAP (glial fibrillary acidic protein)-positive progenitors contribute a subset of smooth muscle cells (green) in the thoracic aorta of postnatal day 14 mice. This study suggests a developmental heterogeneity of smooth muscle cells within the same vascular segment. (See pages 1231–1238.)



 Announcement from our Editor-in-Chief, Dr. Alan Daugherty

ATVB is pleased to announce that we are now considering Research Letters for publication. Please visit https://www.ahajournals.org/atvb/article-types for additional information. 
Editor's Pick

Editor's Pick

ATVB_cover_May 2020_Fig 01
 
Identification of a plasma microRNA profile associated with venous thrombosis

Alba Rodriguez-Rius, Sonia Lopez, Angel Martinez-Perez, Juan Carlos Souto, Jose Manuel Soria

Editor's Note:
This article reports a plasma miRNA profile in members of the Genetic Analysis of Idiopathic Thrombophilia 2 (GAIT-2) population (n=935): a 4-miRNA (hsa-miR-126-3p, hsa-miR-885-5p, hsa-miR-194-5p and hsa-miR-192-5p) plasma profile is associated with venous thrombosis, which may be important in predicting the risk for this serious condition.

https://www.ahajournals.org/doi/10.1161/ATVBAHA.120.314092  

 

 

Featured Articles

ATVB_cover_May 2020_Fig 02

Our study identified TMEM55B as a regulator of non-HDL cholesterol through effects on LDLRlysosomal decay, a finding that can inform the development of novel LDL lowering drugs for cardiovascular disease.

https://www.ahajournals.org/doi/10.1161/ATVBAHA.120.314033

 

 

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Chronic kidney disease (CKD) affects millions yet treatments are limited. Here, Gupta et al. show that inhibition of gut microbe-dependent generation of TMAO attenuates renal functional decline and fibrosis in a CKD model.

Targeted inhibition of gut microbial TMAO production reduces renal functional impairment and fibrosis in a murine model of chronic kidney disease

https://www.ahajournals.org/doi/10.1161/ATVBAHA.120.314139  


 

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