Cardiovascular Health in Turner Syndrome

Published: September 24, 2018

DNA with scientific background
  • This Scientific Statement provides updated information about the diagnosis and treatment of cardiovascular diseases in Turner Syndrome (TS).
  • TS is mainly characterized by obstructive left-sided congenital heart defects (CHDs) – including coarctation of the aorta, bicuspid aortic valve (BAV), mitral valve anomalies, hypoplastic left heart syndrome, and partial anomalous pulmonary vein return – that are rare in the female population and should increase clinical suspicion for TS. Genetic testing for TS should be considered in females with these abnormalities.
  • Health care professionals should monitor patients for any underlying predisposition to metabolic abnormalities, including dyslipidemia, type II diabetes, obesity and hyperuricemia. These can exacerbate hypertension in children with TS as well as coronary artery disease, myocardial infarction and stroke in adults with TS.