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2018 Distinguished Scientist -
Lawrence J. Appel, MD, MPH, FAHA

Lawrence J. Appel, MD, MPH, FAHALawrence J. Appel, MD, MPH, FAHA
C David Molina, MD, MPH Professor of Medicine and
Director, Welch Center for Prevention, Epidemiology, and Clinical Research
Johns Hopkins University School of Medicine
Baltimore, Md.

Dr. Appel is the C. David Molina Professor of Medicine and Director of the Welch Center for Prevention, Epidemiology and Clinical Research, a joint program of the Johns Hopkins University School of Medicine and the Bloomberg School of Public Health. Dr. Appel holds a primary faculty appointment in the Division of General Internal Medicine with joint appointments in Epidemiology, International Health, and Nursing. In addition, he directs the ProHealth Clinical Research Unit in West Baltimore.

The focus of Dr. Appel’s investigative career is the conduct of clinical, epidemiologic, and translational research pertaining to the prevention of high blood pressure, cardiovascular-kidney diseases, and other chronic conditions. He has conducted over 50 studies and published over 400 papers. Many of his research findings have had a substantial influence on health and health care policy. His principal lines of research are:

  • controlled feeding trials, such as the DASH trial, which test optimal dietary strategies to lower blood pressure and cardiovascular risk;
  • behavioral intervention trials, such as the POWER trial, which test novel strategies to accomplish lifestyle modification, often focused on obesity;
  • trials and observational studies, such as AASK and CRIC, which identify risk factors for the progression of chronic kidney disease and its complications.

Dr. Appel has also been actively involved in shaping health care policy. He was a member of the 2005 and 2010 U.S. Dietary Guidelines Scientific Advisory Committees. For the American Heart Association, he has chaired its Nutrition Committee and its Council on Lifestyle and Cardiometabolic Health. He has served on several NIH and Institute of Medicine Committees and chaired the committee that set dietary reference intakes for sodium, potassium, and water. Among his awards are membership in the Association of American Physicians and the National Academy of Medicine (formerly Institute of Medicine).