Maternal and Infant Health HERN
Coordinating Center
The University of Alabama at Birmingham
P3 (Pregnancy and Postpartum/Preconception) EQUATE (Enhancing Access and Quality to Achieve Equitable Maternal and Infant Health)
Coordinating Center Principal Investigator: Alan Tita, MD, PhD, MPH

Research Focus:
Developing evidence for prevention/ screening
guideline to help educate women how poor
sleep can hurt their heart.
Center Director:
Lori Mosca, MD, MPH, PhD, FAHA
Marie Pierre St-Onge, PhD, FAHA
Training Director:
Anne Taylor, MD
Brooke Aggarwal, EdD, MS, CHES
Principal Investigators:
- Sanja Jelic, MD
The Effects of Sleep Restriction on Endothelial Activation in Pre- and Post-Menopausal Women - Marie Pierre St-Onge, PhD, FAHA
Impact of Sleep Restriction on Cardio Metabolic Risk Factors in Pre- vs Post-menopausal Women - Brooke Aggarwal, EdD, MS, CHES
Sleep and Cardio Metabolic Risk in Different Life Stages in a Diverse Population of Women

Research Focus:
Studies will help identify at-risk heartfailure patients on the basis for sex
differences and the prevention strategies to help them.
Center Director:
Pamela Ouyang, MBBS, FAHA
Training Director:
Erin Michos, MD, MHS, FAHA
Principal Investigators:
- David Kass, MD, FAHA
Female Sex-Hormones and Cyclic GMP-PKG Modulation of Cardiac Disease and Metabolism - Sanjiv Shah, MD, FAHA
Role of Female Sex and Hormone Status on HFpEF Pathophysiology and Therapy - Wendy Post, MD, MS and
Dhananjay Vaidya, MBBS, PhD, MPH
Sex Differences in Hormonal and Cyclic GMP Dependent Pathways to Heart Failure with Preserved Ejection Fraction

Research Focus:
Researchers will examine which pregnancy-related signals identify women at highest risk for future cardiovascular disease and guide novel interventions to help them.
Center Director:
Carl Hubel, PhD
Training Director:
James Roberts, MD
Principal Investigators:
- Robert Powers, PhD
The Influence of Pregnancy on Future Vascular Dysfunction and Atherosclerosis -
Carl Hubel, PhD
Glycocalyx Pathways Linking Pregnancy Profile with Microvascular Dysfunction Postpartum - Janet Catov, PhD, MS
The Placenta as a Window to Maternal Microvascular Disease Risk