Maternal and Infant Health HERN

July 2022 - July 2026

Coordinating Center

The University of Alabama at Birmingham

P3 (Pregnancy and Postpartum/Preconception) EQUATE (Enhancing Access and Quality to Achieve Equitable Maternal and Infant Health)

Coordinating Center Principal Investigator: Alan Tita, MD, PhD, MPH

Columbia University Logo

Research Focus: 
Developing evidence for prevention/ screening guideline to help educate women how poor sleep can hurt their heart.

Center Director:
Lori Mosca, MD, MPH, PhD, FAHA
Marie Pierre St-Onge, PhD, FAHA

Training Director:
Anne Taylor, MD
Brooke Aggarwal, EdD, MS, CHES

Principal Investigators:

  • Sanja Jelic, MD
    The Effects of Sleep Restriction on Endothelial Activation in Pre- and Post-Menopausal Women

  • Marie Pierre St-Onge, PhD, FAHA
    Impact of Sleep Restriction on Cardio Metabolic Risk Factors in Pre- vs Post-menopausal Women

  • Brooke Aggarwal, EdD, MS, CHES
    Sleep and Cardio Metabolic Risk in Different Life Stages in a Diverse Population of Women


John Hopkins University and Medicine

Research Focus: 
Studies will help identify at-risk heartfailure patients on the basis for sex differences and the prevention strategies to help them.

Center Director:
Pamela Ouyang, MBBS, FAHA

Training Director:
Erin Michos, MD, MHS, FAHA

Principal Investigators:

  • David Kass, MD, FAHA
    Female Sex-Hormones and Cyclic GMP-PKG Modulation of Cardiac Disease and Metabolism

  • Sanjiv Shah, MD, FAHA
    Role of Female Sex and Hormone Status on HFpEF Pathophysiology and Therapy

  • Wendy Post, MD, MS and Dhananjay Vaidya, MBBS, PhD, MPH
    Sex Differences in Hormonal and Cyclic GMP Dependent Pathways to Heart Failure with Preserved Ejection Fraction


Magee Woman's Research Institute

Research Focus: 
Researchers will examine which pregnancy-related signals identify women at highest risk for future cardiovascular disease and guide novel interventions to help them.

Center Director:
Carl Hubel, PhD

Training Director:
James Roberts, MD

Principal Investigators:

  • Robert Powers, PhD
    The Influence of Pregnancy on Future Vascular Dysfunction and Atherosclerosis

  • Carl Hubel, PhD
    Glycocalyx Pathways Linking Pregnancy Profile with Microvascular Dysfunction Postpartum

  • Janet Catov, PhD, MS
    The Placenta as a Window to Maternal Microvascular Disease Risk