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Recommendation on Design, Execution, and Reporting of Animal Atherosclerosis Studies

  • Animal studies are a foundation for defining mechanisms of atherosclerosis and potential drug targets in cardiovascular diseases.
  • Similar studies designed and conducted with different animal models can give conflicting results, which limits the ability to extrapolate the results to understanding the human disease.
  • This statement aims to serve as a how-to resource for researchers as they design, develop, conduct, and interpret animal studies.

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