ISC17 Science News: Late-Breaking
Clinical Trials and Oral Abstracts

International Stroke Conference 2017

Nursing Symposium & Pre-Con Symposia: Feb. 21, 2017
Sessions: Feb. 22–24, 2017
George R. Brown Convention Center | Houston, TX


 
Data and abstracts will be posted after the presentation time.

Featured Science from Wednesday, Feb. 22

Main Event I: Opening Session
10:30 a.m. to 12:00 p.m. - Hall C

Head Position in Stroke Trial: An International Cluster Cross-over Randomized Trial
Craig S Anderson | George Institute of Global Health, Sydney NSW, Australia

RESULTS: Specific head positioning in acute stroke is of questionable value.

Aster Trial: Contact Aspiration versus Stent Retriever Front Line for Recanalisation in Acute Cerebral Infarction
Bertrand Lapergue | Foch Hospital and Versailles Saint Quentin en Yvelines University, Suresnes, France

RESULTS: Stent retriever and contact aspiration demonstrate similar safety and efficacy in acute cerebral infarction

Prospective, Multi-Center Study of Flow Diversion for Small and Medium-Sized Aneurysms: Results of the Premier Trial
Ricardo A Hanel | Baptist Neurological Institute, Jacksonville, FL

RESULTS: Flow diverter technology is safe and effective.

Featured Science from Thursday, Feb. 23

Thursday Main Event
11:00 a.m. to 12:00 p.m. - Hall C

Intensive Versus Guideline Antiplatelet Therapy For Preventing Recurrence In Patients With Acute Ischaemic Stroke Or TIA: Main Results From The Triple Antiplatelets For Reducing Dependency In Ischaemic Stroke (TARDIS) Trial
Philip M Bath | University of Nottingham, Nottingham, United Kingdom

RESULTS: Neutral results: stroke recurrence was not lower; bleeding increased with intensive antiplatelet therapy.

Cilostazol Versus Aspirin in Ischemic Stroke Patients With Intracerebral Hemorrhage or Multiple Microbleeds
Sun U. Kwon Sr. | Asan Medical Center, Seoul, Republic of Korea

RESULTS: Stroke rates were less with cilostazol than aspirin, but more MI occurred with cilostazol.

Resumption of Oral Anticoagulation After Intracerebral Hemorrhage is Associated With Decreased Mortality and Favorable Functional Outcome
Alessandro Biffi | Massachusetts General Hospital, Boston, MA

RESULTS: The favorable findings in both non-lobar and lobar ICH indicate a need for more randomized clinical trials.

Efficacy and Safety of Nimodipine in Vascular Mild Cognitive Impairment: A Randomized Placebo Controlled Trial
Huaguang Zheng | Capital Medical University, Beijing Tiantan Hospital, Beijing, China

RESULTS: Nimodipine was no better than placebo in preventing cognitive decline.


 

Second Generation Hydrogel-coated Coils for the Endovascular Treatment of Intracranial Aneurysms: Final Results of a Randomized Controlled Trial
Christian Taschner | University Hospital Freiburg, Freiburg, Germany

RESULTS: Compared to standard platinum coils, there were fewer adverse events at 18 months with the hydrogel-coated coils.

Late-Breaking Science Oral Abstracts I
1:30 p.m. to 3:00 p.m. - Grand Ballroom B

Ticagrelor versus Aspirin in Acute Stroke or Transient Ischemic Attack of Atherosclerotic Origin
Pierre Amarenco | Paris Diderot University, Paris, France

RESULTS: At 90 days, ticagrelor prevented more strokes, MIs, and deaths than aspirin in patients with acute stroke or transient ischemic attack of atherosclerotic origin.

E-cigarette Exposure Alters Brain Glucose Utilization and Stroke Outcome
Ali E. Sifat |Texas Tech University Health Science Center School of Pharmacy, Amarillo, TX

RESULTS: Vaping is not safer than smoking; stroke risk may be similar if not higher.

Shake, Rattle & Roll Trial - Improving Blood Pressure Control Among African Americans
Mai N Nguyen-Huynh | Kaiser Permanente, Oakland, CA

RESULTS: A culturally tailored lifestyle approach improved BP control at 12 months.

Safety and Feasibility of Combination of Ticagrelor and Aspirin in Patients With Minor Stroke or TIA :Interim Analyses of the Platelet Reactivity in Acute Stroke or Transient Ischemic Attack (PRINCE) Trial
Yilong Wang | Capital Medical University, Beijing Tiantan Hospital, Beijing, China

RESULTS: Adverse events led to more medication discontinuation in the ticagrelor arm compared to the clopidogrel arm.

Rapid Increase in Endovascular Thrombectomy for Acute Ischemic Stroke in the United States: Data From Get With the Guidelines-Stroke
Eric E Smith | University of Calgary, Calgary, AB, Canada

RESULTS: Randomized controlled trial results and updated guidelines prompted more use of endovascular thrombectomy.

Interhospital Transfer Prior to Thrombectomy is Associated With Delayed Treatment and Worse Outcome in the STRATIS Registry
Michael T Froehler | Vanderbilt University, Nashville, TN

RESULTS: Strategies to spot large vessel occlusion and use endovascular-capable centers may improve outcomes.

Featured Science from Friday, Feb. 24

Closing Main Event
10:30 a.m. to 12:30 p.m. - Hall C

Randomized Trial of Hemostatic Therapy for 'Spot Sign' Positive Intracerebral Hemorrhage: Primary Results From the SPOTLIGHT/STOP-IT Study Collaboration
David J. Gladstone | University of Toronto, Toronto, ON, Canada

RESULTS: Emergency CT angiography has prognostic value in acute intracerebral hemorrhage, but treatment with rFVIIa did not improve outcomes.

Randomized Controlled Trial of Early versus Delayed Statin Therapy in Patients With Acute Ischemic Stroke
Shinichi Yoshimura | Hyogo College of Medicine, Nisinomiya City, Japan

RESULTS: Stroke disability was not reduced with early statin treatment for acute ischemic stroke.

A Randomized Double-Blind Pilot Study Assessing Vagus Nerve Stimulation (VNS) During Rehabilitation for Improved Upper Limb Motor Function After Stroke
Jesse Dawson | University of Glasgow, Glasgow, United Kingdom

RESULTS: Vagus Nerve Stimulation is safe and feasible for stroke rehabilitation; arm function improved.