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Science News from ESC 2014

European Society of Cardiology
August 30 – Sept. 3, 2014 | Barcelona, Spain

Hot Line I – Cardiovascular Disease: Novel Therapies


Elliott Antman, MD, FAHA, Mariell Jessup, MD, FAHA, and Mark Creager MD, FAHA discuss the science that was presented during Hotline I Cardiovascular Disease Novel Therapies at ESC 2014 in Barcelona, including PARADIGM HF, CONFIRM, MORE-CRT, COPPS-2.

PARADIGM-HF (PDF) | See more in-depth analysis on this trial
Results of the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial
 

NECTAR-HF (PDF)
A randomized controlled trial of vagal stimulation for the treatment of systolic heart failure: NEural Cardiac TherApy foR Heart Failure
 

CONFIRM-HF (PDF)
Effect of ferric carboxymaltose on functional capacity in patients with heart failure and iron deficiency
 

MORE-CRT (PDF)
Cardiac resynchronization therapy with a novel quadripolar lead decreases complications at six months: preliminary results
 

POPE 2 (PDF)
Colchicine for Post- operative Pericardial Effusion: The post-operative pericardial effusion study. A multicenter, double-blind, randomized trial
 

COPPS 2 (PDF)
COlchicine for Prevention of the Post-pericardiotomy Syndrome and Post-operative Atrial Fibrillation
 

Hot Line II – Coronary Artery Disease and Lipids


Elliott Antman, MD and Rose Marie Robertson, MD discuss the science presented for Hotline II at ESC 2014 in Barcelona, including SOLID, SIGNIFY, and ODYSSEY.

SOLID-TIMI 52 (PDF)
The Stabilization Of pLaques usIng Darapladib-Thrombolysis in Myocardial Infarction 52 trial: Primary Results
 

SIGNIFY (PDF)
Ivabradine in patients with stable coronary artery disease without clinical heart failure
 

ODYSSEY COMBO II (PDF)
Efficacy and safety of alirocumab in high cardiovascular risk patients with inadequately controlled hypercholesterolaemia on maximally tolerated daily statin
 

ODYSSEY FH I & FH II (PDF)
Efficacy and safety of alirocumab in patients with heterozygous familial hypercholesterolaemia not adequately controlled with current lipid-lowering therapy
 

ODYSSEY LONG TERM (PDF)
Long-term safety, tolerability and efficacy of alirocumab versus placebo in high cardiovascular risk patients: first results from 2,341 patients.
 

LISTEN (PDF)
The differences of the effects on lipid-lowering actions and glucose metabolisms between rosuvastatin and atorvastatin in Japanese diabetic patients with hyperlipidemia.
 

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