Programming - Hypertension Scientific Sessions

September 4–7, 2025
Marriott Baltimore Waterfront | Baltimore, Maryland

#Hypertension25 Abstracts 2025 Poster Sessions (PDF)

Hypertension 2025 Final Schedule

All times below are Eastern Daylight Time (EDT) (UTC -4)

Wednesday, Sept. 3 Activities
Time	Activity
6:00 pm to 7:00 pm	Hypertension Journal Meet the Editors Networking Event Dover A-C (open to all)
7:00 pm to 9:00 pm	Opening Reception and Networking Session Dover A-C (Ticketed Event) (Add Ticket to your Registration)

Thursday, September 4 Activities
Time	Activity
7:30 am to 8:00 am	Welcome and Opening Remarks Grand Ballroom 1-5 7:30 American Heart Association Presidential Remarks Stacey E. Rosen, MD, FAHA President, American Heart Association 7:45 Hypertension 2025 Welcome Remarks Jane F. Reckelhoff, PhD, FAHA Chair, Council on Hypertension Steven D. Crowley, MD Vice-Chair, Council on Hypertension Program Chair, Hypertension 2025 Scientific Sessions
8:00 am to 10:00 am	Session 1 Grand Ballroom 1-5 Moderators: Wanpen Vongpatanasin, MD, FAHA, FACC and Steven Crowley, MD 8:00 to 8:35 Keynote: Overview of the 2025 AHA/ACC High Blood Pressure Guideline Daniel W. Jones, MD, FAHA 8:35 to 8:50 The Evidence for Blood Pressure Treatment Goal Paul K. Whelton, MB, MD, MSc and Jordana B. Cohen, MD, MSCE 8:50 to 9:04 Management of the Patient With Stage 1 Hypertension and Low 10 Year CVD Risk Keith C. Ferdinand, MD, FACC, FAHA, FASPC, FNLA, FPCNA (hon.) 9:05 to 9:20 Evaluation and Management of the Patient with Hypertension and CKD or Diabetes Sandra J. Taler, MD, FAHA 9:20 to 9:35 Importance and Opportunity of Team-Based Care Including Remote Monitoring/Management Yvonne Commodore-Mensah, PhD, MHS, BSN, RN, FAHA, FPCNA 9:35 to 10:00 Panel Discussion and Q&A (with all speakers)
10:00 am to 10:30 am	Break
10:30 am to 12:00 pm	Session 2 - Concurrent Sessions A, B and C (Oral Abstract Presentations) Concurrent 2A: Vascular Biology Grand Ballroom 1-5 Moderators: Michael J. Ryan, PhD and Sarah Lindsey, PhD 10:30 a.m. Invited Lecture: Vascular Smooth Muscle O-GlcNAc Transferase (OGT) is Sensitive to Biomechanical Stress and is Protective Against Arterial Stiffness Cameron McCarthy, PhD, FAHA 001 11:00 AM Investigating Oxidative Stress and Endothelial Dysfunction Through Proteomics in Hypertensive African American Adults Nekesa Oliver 002 11:15 AM Aberrant Endothelial Progranulin Secretion Modulates Endothelial AMPK to Protect the Vasculature in Hypertension Tyler Beling 003 11:30AM Smooth Muscle Cell-Specific Npr1 is Crucial for Regulating Blood Pressure and Vasorelaxation Kailash N Pandey 004 11:45 AM Cell-Free Mitochondrial DNA Drives PANoptosis in the Perivascular Adipose Tissue Promoting Vascular Dysfunction in Mice Exposed to Chronic Stress Rinaldo Rodrigues dos Passos Concurrent 2B: Pregnancy & Preeclampsia Grand Ballroom 7-10 Moderators: Denise C. Cornelius, PhD, FAHA, and S. Ananth Karumanchi, MD 10:30 AM Invited Lecture: Beyond Anatomy: Advanced Ultrasound Techniques to Detect Placental Dysfunction in Preeclampsia Carolyn Bayer, PhD 005 11:00 AM A Failure to Increase Glomerular Filtration Rate during Pregnancy Results in a Greater Susceptibility to Kidney Damage and Renal Impairment in Response to a Postpartum High Salt Diet John Henry H Dasinger 006 11:15 AM APOL1 Risk Variants in Preeclampsia: From Mechanistic Insights to Therapeutic Opportunities Vivikta Rao 007 11:30 AM Maternal Leptin Programming Induces Sex-Specific Hypertension and Endothelial Dysfunction in Male Mice Offspring Mona Elgazzaz 008 11:45 AM Failure of Cardiac Adaptation to Pregnancy in a Superimposed Preeclampsia Model Potentially Leads to Placental Insufficiency and Fetal Growth Restriction Denise C Cornelius Concurrent C: Blood Pressure Monitoring Grand Ballroom 6 Moderators: Adam Bress, PharmD, MS and Ruth-Alma Turkson-Ocran, PhD, MPH, APRN 10:30 AM Invited Lecture Blood Pressure Monitoring Tammy Brady, MD, PhD 009 11:00 AM Concordance between home and ambulatory awake blood pressure in older adults with hypertension: Findings from AMBROSIA-HOME study Lama Ghazi 010 11:15 AM Machine Learning and Longitudinal Blood Pressure Data Enhance Prediction of Hypertensive Disorders of Pregnancy Sara Sauer 011 11:30 AM Accuracy of Visually Estimated Mean Home Blood Pressure: Estimating Yield of Eyeballed BP Study Jesslin Abraham 012 11:45 AM Promoting Access to Self-Measured Blood Pressure Monitoring in Public Libraries Gabriella Pandolfelli
12:00 pm to 1:00 pm	Session 3 Meet the Guideline Keynote Speaker and Panel Networking Event (Early career focused. Boxed lunches will be served. Attendance is limited; First come, first served)
1:00 pm to 1:30 pm	Sponsored Learning Studio Astra Zeneca Grand Ballroom 6 (Includes Lunch) Decoding a Silent Threat: Uncovering Aldosterone's Impact on Hypertension and Cardiovascular Morbidity Nearly half of U.S. adults with hypertension (HTN) have uncontrolled blood pressure, despite taking multiple antihypertensive medications. This persistent challenge greatly increases their risk of cardiovascular and kidney complications, as well as mortality. We’ll explore the often overlooked role of aldosterone as a key pathophysiological driver of HTN, which raises the question—Could novel treatments targeting aldosterone production be warranted for patients with HTN who remain uncontrolled? Presented by: Dr. Ambarish Pandey, MD, MSCS
1:30 pm to 3:00 pm	Session 4 Grand Ballroom 1-5 Moderators: Jane F. Reckelhoff, PhD, FAHA, and Steven D. Crowley, MD 1:30 – 2:00 PM Harriet Dustan Lecture: Sex Differences in Immune-Mediated Hypertension: Why Menopause Matters Heddwen L. Brooks, PhD 2:00 - 3:00PM Hypertension Highlights Oral Abstract Presentations RF01 2:01 PM Association of Antihypertensive Medications with Orthostatic Hypotension among Very Old Adults: Findings from the ARIC Study Md Marufuzzaman Khan RF02 2:07 PM High Salt Intake Enhances the REVERSIR-Induced Recovery of Blood Pressure after Angiotensinogen siRNA Treatment Edwyn Omar Cruz-Lopez RF03 2:13 PM Trends in Untreated Elevated Blood Pressure in Routine Clinical Practice, 2014-2024: a Nationwide Study Jay B Lusk RF04 2:19 PM A peptoid derivative of alpha-calcitonin gene related peptide improves cardiac function in pressure-overload heart failure mice Ambrish Kumar RF05 2:25 PM There is Heterogeneity of Aldosterone Dysregulation and Clinical Outcomes in Patients with the Lateralizing or Unilateral Primary Aldosterone Phenotype according to the Magnitude of Suppression of Contralateral Aldosterone Secretion Albert Botchway RF06 2:31 PM Sociodemographic Influences on Hypertension Prevalence Across New York Counties: A Multivariate Regression Analysis Vishakha Modak RF07 2:37 PM Retinoic Acid, Insulin-like Growth Factor and Nerve Growth Factor are Locally Activated in Renal Arteriolar Hypertrophy caused by Renin-Angiotensin System Inhibition Manako Yamaguchi RF08 2:43 PM Predicting Peptide-Human Leukocyte Antigen and Isolevuglandin Immunogenicity in Hypertension Using Structure-based Deep Learning Kuniko Hunter RF09 2:49 PM Artificial Intelligence-Enhanced Electrocardiography for the Detection and Prediction of Arterial Hypertension: A Systematic Review Jose Arriola-Montenegro RF10 2:55 PM Cardiometabolic Dysfunctions in the Offspring of Fructose-Overloaded Rats: role of the Cholinergic Anti-Inflammatory Reflex Katia De Angelis
3:00 pm to 3:30 pm	Break
3:30 pm to 5:30 pm	Session 5 Concurrent A and B (Trainee Advocacy Committee Oral Abstract Sessions) Concurrent C (Clinical Science/Clinical Practice Sessions) Concurrent 5A: Unlocking the Cardiometabolic Code of Hypertension Grand Ballroom 1-5 Moderators: Mona Elgazzaz, MD, PhD and Laena Pernomian, PhD 013 3:30 PM Comparative Improvement in Cardiovascular Outcomes of Individual SGLT2i Drugs in Individuals with Type 2 Diabetes at Moderate Cardiovascular Risk Anum Zehra 014 3:45 PM Female Sex Chromosomes: A likely Origin for Sex Differences in the Mechanisms of Obesity-associated Hypertension Candee Barris 015 4:00 PM Activated CD8+HLA-DR+ T Cells as Immune Biomarkers of Metabolic Dysfunction and Cardiovascular Risk in Prediabetes Fatema Alrashed 016 4:15 PM Remodeling of perineuronal nets and astrocyte activation in the mediobasal hypothalamus in obesity-related hypertension Himanshu Verma 017 4:30 PM Obesity Impairs Transcriptional Upregulation of Fatty Acid β-oxidation in Response to Fasting Silas A Culver 018 4:45 PM Semaglutide Use Associated with Lower Blood Pressure in Patients with Cardiometabolic Multimorbidity: Real-World Evidence from the All of Us Research Program Lydia Vassiliadi 019 5:00 PM Differential Impact of High-Fat and High-Fat High-Sucrose Diets on Sympathetic and Cardiovascular Function in Mice Deng-Fu Guo 020 5:15 PM Risk of Ventricular Arrhythmia Development due to Hypoglycemia in Diabetic Patients Sana Ahmed Concurrent 5B: Molecular Highways: New Paths in Vascular Biology Grand Ballroom 7-10 Moderators: Natalia M. Mathieu, PhD and Emma Wabel, BS, BA 021 3:30 PM Blood Pressure Magnitude as a Modulator of Perivascular Adipose Tissue Fibrotic Response C. Javier Rendon 022 3:45 PM Lifelong Training Mitigates Age-Related Vascular Stiffness Independent Of Blood Pressure Lukas Kloesges 023 4:00 PM Selective Expression of Gαq-Biased AT1R Mutant in Vascular Smooth Muscle Causes Hypertension and Vascular Dysfunction Nisita Chaihongsa 024 4:15 PM Xist Downregulation Promotes Arterial Stiffening and Endothelial Dysfunction in Obesity Elizabeth Aboagye 025 4:30 PM Arterial Stiffness and Endothelial Dysfunction can be reversed with Healthy Eating in Obese Children Mariano Duarte 026 4:45 PM Genome Sequencing Identifies Rare Mendelian Segregating Variants in Vascular Regulatory Genes in Childhood-Onset Essential Hypertension Edmond Wonkam Tingang 027 5:00 PM Vascular Smooth Muscle Cell Plasticity in Human Hypertension Is Defined by a Distinct Oxidative Proteome and Downregulation of Nox5-Targeting miRNAs Livia L Camargo 028 5:15 PM Increased Microglia-Vascular Interactions and Reduced Resting Cerebral Blood Flow are Associated with Cognitive Decline During Arterial Stiffening Cayla Jeff Concurrent 5C (Clinical Science/Clinical Practice Sessions) 3:30 to 4:30 p.m. Concurrent 5C1: Transforming Hypertension Diagnosis and Management with Artificial Intelligence Grand Ballroom 6 Moderators: Erica S. Spatz, MD, MHS and Brandy M. Wynne, MS, PhD, FAHA 3:30 AI in Hypertension Management: Game-Changer or Hype? Alexander Chang, MD, MS 3:40 Cuffless BP Measurement Devices: Are We Ready to Embrace Them? Alta Schutte, PhD 3:50 Debate: I'm All In for AI in Hypertension Management: The Future Is Now! Arunashis Sau, MBBS, PhD 4:00 Debate: AI in Hypertension Management? Let's Pump the Brakes! Kelsey B. Bryant, MD, MPH, MS 4:10-4:30 Panel Discussants Erica S Spatz, MD, MHS Mattias Brunström, MD, PhD Eugene Yang, MD 4:30 to 5:30 p.m. Concurrent 5C2: Managing Hypertension: From Pregnancy to Postpartum and Beyond Grand Ballroom 6 Moderators: Natalie Bello, MD, MPH and James M. Luther, MD, MSCI 4:30 Key Takeaways from AHA Statement: Hypertension in Pregnancy and Postpartum: Current Standards and Opportunities to Improve Care Malamo Countouris, MD, MS 4:42 Mastering Antepartum BP Management: What You Need to Know Maria Carolina Gongora, MD 4:54 Postpartum Hypertension Management: Optimizing Care and Outcomes Emily S. Lau, MD, MPH 5:06 Hypertensive Disorders of Pregnancy: What to Keep in Mind for the Long Game Jennifer Lewey, MD, MPH 5:18 to 5:30 Panel Discussion Alisse Hauspurg, MD, MS Zainab Mahmoud, MD, MSc Megan McLaughlin, MD, MPH
5:30 pm to 7:00 pm	Poster Session 1 and Reception (#Hypertension25 Poster Sessions PDF) Harborside Ballroom Includes the TAC Poster Competition This session is sponsored by Hypertension, an American Heart Association Journal
6:30 pm to 8:30 pm	Sponsored Learning Studio Clinical Care Options, LLC Dover A-C (Includes Dinner) Pressure Points in Resistant Hypertension: Pioneering New Pathways to Control the Uncontrollable 6:30 p.m to 7:00 p.m. – Registration & Dinner 7:00 p.m. to 8:30 p.m. – Learning Studio Provided by Clinical Care Options, LLC Supported by an educational grant from AstraZeneca Pharmaceuticals

Friday, Sept. 5 Activities
Time	Activity
7:00 am to 8:00 am	Session 6 Inside the AHA's Research Enterprise: Grant Funding and Other Opportunities Grand Ballroom 7–10 Presenters: Glenn Dillon, PhD and Richard Wainford, PhD
7:15 am to 7:45 am	Sponsored Learning Studio Grand Ballroom 6 Recor Medical (Included breakfast) Guidelines and future of hypertension: where does Renal Denervation fit? This session will explore evolving hypertension guidelines, real-world evidence, and unmet needs in patient care. Experts will discuss how renal denervation (RDN) fits into current treatment pathways and consider future integration with pharmacologic and lifestyle strategies. Presenters: Dr. Michael Bloch, Dr. Angela Brown, Jordan King, PA-C, Dr. Wissam Garib
8:00 am to 9:00 am	Session 7 Recent Advances in Hypertension: GLP-1 Agonists Grand Ballroom 1-5 Moderators: Jane F. Reckelhoff, PhD, FAHA and Steven D. Crowley, MD 8:00 Understanding the GLP-1 Receptor as a Drug Target — Physiology Chasing Pharmacology David D'Alessio, MD 8:30 Combination Therapies in Kidney Disease: Revolutionizing Cardiovascular-Kidney-Metabolic Health Janani Rangaswami, MD, FACP, FAHA
9:00 am to 10:30 am	Poster Session 2 (#Hypertension25 Poster Sessions PDF) With Breakfast Reception Harborside Ballroom
10:30 am to 12:00 pm	Session 8 Concurrent Sessions A, B (Trainee Advocacy Committee Oral Abstract Sessions) Concurrent C (Clinical Practice/Clinical Science) Concurrent 8A - TAC Oral Abstract Award Competition Grand Ballroom 1-5 Moderators: Cameron McCarthy, PhD, FAHA and Monica M. Santisteban, PhD 029 10:30 AM Comprehensive Resistant Hypertension Clinic Improves Access to Care and Blood Pressure Control Lilit Vardanyan 030 10:45 AM “Female” Gut Commensal Akkermansia muciniphila Lowers Blood Pressure in Male Spontaneously Hypertensive Rats Tania Akter Jhuma 031 11:00 AM Agreement between sleep blood pressure on home blood pressure monitoring versus ambulatory blood pressure monitoring: Findings from Better BP study Lama Ghazi 032 11:15 AM Cardiometabolic Control by Angiotensin II Type 1 Receptor-Expressing Agouti-Related Peptide Neurons Samuel Lawton 033 11:30 AM AI-Augmented Prediction of Hypertensive Emergency Outcomes Using National Inpatient Data: A Machine Learning Approach to Risk Stratification Ashish Sharma 034 11:45 AM Endothelial Cell Mineralocorticoid Receptor as a Nexus for Leptin-Aldosterone Crosstalk in Salt Sensitivity of Blood Pressure in Young Female Mice Ishara M.G. Menik Concurrent 8B - Let's Get Specific: Sex Differences, Dimorphisms, and Disparities in Hypertension Grand Ballroom 7-10 Moderators: Candee Barris, BS and Sara M. Zarate, PhD 035 10:30 AM Sex-Differences in Tryptophan Metabolism in a Rat Model of Circadian Disruption Mary Latimer 036 10:45 AM Area Deprivation, Social Vulnerability, and Incident Hypertension in Men and Women at Midlife: The Coronary Artery Risk Development in Young Adults (CARDIA) Study Allison E. Gaffey 037 11:00 AM Renal Denervation Reduces Salt Preference In Female Spontaneously Hypertensive Rats Babatunde Anidu 038 11:15 AM Racial and Ethnic Disparities in Shared Decision-Making Around Hypertension Among Women of Reproductive Age: Insights from the SAFE HEART Study Asma Rayani 039 11:30 AM Smooth Muscle Cell Estrogen Receptor Alpha Regulates Aging-Associated Arterial Stiffness via Sex-Specific Mechanisms Casey Turner 040 11:45 AM Impact of High Salt Diet on T Cells in Male and Female Mice During Lymphocytic Choriomeningitis Virus Infection Sophia Blessinger 10:30 to 11:30am Concurrent Session 8C - Unpacking the 2025 AHA/ACC High Blood Pressure Guideline: What’s New and What It Means for Your Practice (Clinical Science/Clinical Practice track programming) Grand Ballroom 6 Moderators: Adam Bress, PharmD, MS and Heather M. Johnson, MD, MS, MMM, FAHA 10:30 – 10:40 2025 AHA/ACC High Blood Pressure Guideline: The 12 Key Takeaways You Can't Miss Karol E. Watson, MD, PhD, FACC 10:40 – 10:50 Turning Guidelines into Practice: How Do We Make It Happen? Donald M. Lloyd-Jones, MD ScM 10:50- 11:00 Using PREVENT to Personalize Blood Pressure Management Sadiya S. Khan, MD, MSc 11:00 – 11:10 Real world applications of using PREVENT for Blood Pressure Management Eugene Yang, MD, MS 11:10-11:30 Panel Discussion Kristi Reynolds, PhD, MPH, FAHA Jan Basile, MD FAHA Hokyou Lee, MD, PhD, FAHA Mattias Brunström, MD, PhD
12:00 pm to 1:30 pm	Session 9 CHAMP Lunch Event (You must preregister prior to the conference) Dover A-C
12:30 pm to 1:00 pm	Sponsored Learning Studio Medtronic Grand Ballroom 6 (includes lunch) Transforming Hypertension Care: The Symplicity™ Blood Pressure Procedure Join us! Medtronic sponsored Learning Studio, lunch provided, for an insightful session on Transforming Hypertension Care: The Symplicity™ Blood Pressure Procedure - an adjunctive option for managing hypertension. Hear from leading experts as they discuss the latest guidelines, clinical evidence, and patient selection strategies. Engage in interactive discussions and real-world case studies that highlight best practices and shared decision-making. Don’t miss this opportunity to enhance your knowledge and improve patient care! Learn more and be part of the future of hypertension management! Speakers: Yvonne Commodore-Mensah, PhD, MHS, RN, FAAN, Michael Bloch, MD, Brian Fulton, MD and Raven Voora, MD
1:30 pm to 3:00 pm	Session 10 Concurrent Sessions A&B (Invited Lecture followed by Oral Abstract Presentations) Concurrent Session C (Clinical Practice/Clinical Science) Concurrent 10A: Oxidative Stress, Inflammation, Immunity and Cytokines Grand Ballroom 1-5 Moderators: Carmen De Miguel, PhD, MS, FAHA and Johannes Stegbauer, MD 1:30 PM Invited Lecture: Angiotensin II-induced Hypertension Promotes Innate Immune Memory and Predisposes to Atherosclerosis Progression Amanda Doran, MD, PhD 041 2:00 PM Impaired Meningeal Lymphatic Drainage and Cognition in DOCA-salt Hypertension Olivia Kelly 042 2:15 PM Microglia Depletion Mitigates Sympathetic Hyperactivity in Chronic Kidney Disease Swati Sharma 043 2:30 PM Endothelin System Activation by Autoantibodies as a Mechanistic Pathway to Lupus-associated Hypertension Helen Butler 044 2:45 PM G6PD-Driven Metabolic Reprogramming Promotes NETosis Formation and Abdominal Aortic Aneurysm Progression Lin Zheng Concurrent 10B: Neurogenic Mechanisms Grand Ballroom 7-10 Moderators: Eric Lazartigues, PhD and Justin L. Grobe, PhD 1:30 PM Invited Lecture: Cognitive Function in Hypertension: Visualization by Advanced MRI Techniques Lorenzo Carnevale, PhD 045 2:00 PM Increased Firing Rate and Interleukin-6 Mediated Disinhibition in Renal-Specific Dorsal Root Ganglion Neurons from Hypertensive Rats Christopher T Banek 046 2:15 PM Lack of Renin within the Nucleus Ambiguus Results in Impaired Vagal Cardioinhibitory Function Kathren Kaminski 047 2:30 PM High Salt-Induced Increases in Renal Interstitial Osmolarity Induces Renal Sensory Nerve Activation Brandi M Wynne 048 2:45 PM Evidence that Bmal1 Regulates Time-of-Day Dependent Control of Autonomic Tone in Rats Megan K Rhoads Concurrent 10C: Rapid-Fire Cases: Burning Questions You’ve Always Wanted to Ask a Hypertension Specialist (Clinical Science/Clinical Practice Sessions) Grand Ballroom 6 Moderators: John Bisognano, MD, PhD and Meena Madhur, MD, PhD, FACC, FAHA Presenters: 1:30 PM Should I Treat this Patient's Hypertension in the Hospital? James M. Luther, MD, MSCI 1:40 PM Early Onset Hypertension: The Devil is in the Details Angela Price, MD 1:50 PM Medical treatment and follow up of Primary Hyperaldosterone in ‘The Zone of Overlap’ Laura Mayeda, MD, MPH and Michael Rose, MD, MPH 2:00 PM A Curious Case of Repeated Hypertensive Urgency Matthew Alexander, MD, PhD, FAHA and Whitney Barham, MD 2:10 PM Blood Pressure: Cause or Effect? Jawad Mir, MD and Eric Judd, MD 2:20 PM From Chronic to Acute: A Hidden Cause Behind Escalating Blood Pressure Jay Lusk, MD, MBA and Alan Hinderliter, MD 2:30 PM Discussion Panelists: Adina Turcu, MD, MS Joseph Flynn. MD, MS Matthew Alexander, MD, PhD, FAHA Daichi Shimbo, MD
3:00 pm to 3:30 pm	Break
3:30 pm to 5:00 pm	Session 11 Annual Hypertension Awards Session Grand Ballroom 1-5 3:30 – 4:00 The Stephanie Watts Award Finalist presentations: Moderators: Monica M. Santisteban, PhD and Benard Ogola, PhD 3:30 PM Sex Differences, Immune Cell Dynamics, and Increased Risk of Hypertension in a Mouse Model of Takotsubo Cardiomyopathy Daniel J. Fehrenbach, PhD 3:40 PM Spatial Analysis of Metabolic Reprogramming and Its Redox Regulation in Salt-Sensitive Hypertension Satoshi Shimada, MD, PhD 3:50 PM Estrogen Loss and Sleep Restriction Disrupt Blood Pressure Rhythms and Vascular Function Bruna Visniauskas, PhD 4:00 – 4:45 Annual Hypertension Awards Moderators: Jane F. Reckelhoff, PhD, FAHA, and Steven D. Crowley, MD 049 4:00 PM New Investigator Award for Japanese Fellows: Effects of Sglt2 Knockout on high salt-induced organ damage in Dahl salt-sensitive hypertensive rats Hiroki Ito 4:15 PM Harry Goldblatt Award for New Investigators: Endothelial Control of Vascular Tone: Local Signals, Systemic Consequences Thiago Bruder do Nascimento, PhD, FAHA
5:00 pm to 5:30 pm	Session 12 The Lewis K. Dahl Memorial Lecture Grand Ballroom 1-5 Moderators: Jane F. Reckelhoff, PhD, FAHA, and Steven D. Crowley, MD From Endocrine, Paracrine to Intracrine Angiotensin II: What Else Is Left for Angiotensin II-Dependent Hypertension Research? Jia L. Zhou, MD, PhD
7:00 pm to 10:00 pm	Trainee Advocacy Mixer Event (Offsite Event) James Joyce 616 President St, Baltimore, MD 21202

Saturday, Sept. 6 Activities
Time	Activity
7:00 am to 7:30 am	Sponsored Learning Studio Idorsia Grand Ballroom 6 (Includes Breakfast) The Next Era in the Treatment of Hypertension Ready for the Next Era in the Treatment of Hypertension? You can help lower difficult to control hypertension with TRYVIO – the first and only dual endothelin receptor antagonist for systemic hypertension- as it takes a different path to lower blood pressure. TRYVIO significantly reduces systolic blood pressure by targeting the endothelin pathway and has a demonstrated long-term safety profile. Visit Idorsia Pharmaceuticals at Booth #2 and #3 and join them on Saturday, September 6th at 7AM for a Learning Studio to learn more about how they are advancing the treatment of hypertension! Presenter: Dr. Michael Bloch
7:30 am to 9:00 am	Session 13 7:30-8AM The Donald Seldin Lecture Grand Ballroom 1-5 Moderator: Thu Le, MD, FAHA Genetic Risk of Chronic Kidney Disease in Special Populations Nora Franceschini, MD, MPH, FAHA 8-8:30 KCVD Early Career Session Grand Ballroom 1-5 Moderators: Thu Le, MD, FAHA and Tianxin Yang, MD, PhD 050 8:00 AM Integrated Multi-Organ Transcriptomic Atlas Reveals Novel Tissue-Specific Pathways in Salt-Induced Hypertension Ratnakar Tiwari 051 8:15 AM Adoptive Transfer of Lupus Patient PBMCs Promotes Salt-Sensitive Hypertension and Kidney Injury in Immunodeficient Mice Mohammad Saleem 052 8:30 AM Innate Immunity-Mediated Mechanisms of Hypertensive Kidney Damage and Dysfunction Hebah Almarshood 053 8:45 AM Microbes Regulate Glomerular Filtration Rate in Health and Chronic Kidney Disease Jiaojiao Xu
9:00 am to 10:00 am	Session 14 Concurrent A, B Oral Abstract Sessions Concurrent C (Clinical Practice/Clinical Science) Concurrent 14A Sex and Gender Differences in Hypertension Grand Ballroom 1-5 Moderators: Kate Denton, PhD and Babbette LaMarca, PhD 054 9:00 AM Sex Differences in Age-associated Cardiac Metabolome Identify Dysregulated Metabolite Cofactors of Epigenetic Enzymes Prerna Kumar 055 9:15 AM Smooth Muscle Cell Estrogen Receptor Alpha Deletion Improves Microvascular Function In Aged Female, But Not Male, Mice Jacqueline Matz 056 9:30 AM Early life circadian stress increases sensitivity to angiotensin II only in male rats Hiruni Aponso 057 9:45 AM Sex Differences, Immune Cell Dynamics, and Increased Risk of Hypertension in a Mouse Model of Takotsubo Cardiomyopathy Daniel J Fehrenbach Concurrent 14B Mineralocorticoid Receptors, Inflammation, Obesity and Cardiovascular Disease Grand Ballroom 7-10 Moderators: John D. Bisognano, MD PhD FAHA and Wanpen Vongpatanasin, MD, FAHA 058 9:00 AM Mineralocorticoid Receptor Signaling in Chronic Kidney Disease-Driven Aortic Stenosis: Role of the Innate Immune Toll-Like Receptor Pathway Tania Sanchez-Bayuela 059 9:15 AM Cardiovascular injury associated with Transient Receptor Potential Melastatin 7 (TRPM7) downregulation and Mg2+ deficiency involve calpain Francisco Rios 060 9:30 AM Non-adipocyte mineralocorticoid receptors are required to abrogate the exacerbated obesogenic response to early life stress in female mice Analia S Loria 061 9:45 AM Baxdrostat Lowers Blood Pressure in Patients with Uncontrolled Hypertension and Chronic Kidney Disease: Results from the FigHTN Phase 2 trial Jamie P Dwyer Concurrent 14C CPCS Session Hypertension Journal Programming Grand Ballroom 6 Moderators: Kelsey Bryant, MD, MPH, Paola Lanza, MD and Jennifer Cluett, MD 9:00 Combining Epithelial Sodium Channel Inhibitor and Mineralocorticoid Receptor Antagonist: Targeted Therapy for Resistant Hypertension in the Young Presenters: Vanessa Le, MS3, Sarah Lee, MS3, and Ekamol Tantisattamo, MD 9:30 Two cases in Pregnancy: Pheochromocytoma and Paraganglioma Presenters: Bernadette Jenner, MD and Prof. Ian Wilkinson
10:00 am to 10:30 am	Break
10:30 am to 12:00 pm	Session 15 Concurrent A, B and C Invited Lectures followed by Oral Abstract Presentations Concurrent 15A - Renin Angiotensin System Grand Ballroom 1-5 Moderators: Maria Luisa S. Sequeira Lopez, MD, FAHA and Curt D Sigmund, PhD, FAHA 10:30 AM Invited Lecture: Novel Perspectives on the Brain Renin-Angiotensin System Pablo Nakagawa, PhD 062 11:00 AM ACE2 Amplification, unlike ACE inhibition, does not cause an increase in plasma renin: potential therapeutic implications Yusuf Shakaib 063 11:15 AM Coordinated Calcium Oscillations Within Juxtaglomerular Cell Clusters: A Central Mediator Of Renin-Angiotensin System Hiroki Yamaguchi 064 11:30 AM Application of Angiotensin-Based Biomarkers Quantified by Mass Spectrometry to Predict Preeclampsia Robin C Shoemaker 065 11:45 AM Precision Medicine for Uncontrolled Hypertension using Angiotensin Based Biomarkers - Algorithm, Cut-Off Values and Real-Life Clinical Data Marko Poglitsch Concurrent 15B Hypertension and Aging Grand Ballroom 7-10 Moderators: Daniela Carnevale, PhD and Richard Wainford, PhD 10:30 AM Invited Lecture: Hypertension and Cognitive Decline Monica Santisteban, PhD 066 11:00 AM Nonlinear Analysis of 24-Hour Blood Pressure in Relation to Cognitive Impairment and Dementia Jesus David Melgarejo 067 11:15 AM Exploration Of Glymphatic Function In Subjects With Controlled Hypertension: a Multimodal Study Sebastiano La Ferla 068 11:30 AM Ang II i.c.v. is Associated with Cognitive Impairment and Tau Phosphorylation in Male Mice in the Absence of Hypertension Sara Zarate 069 11:45 AM Investigating the Role of Olfactory Receptor 558 in Blood Pressure Regulation and Aging Rachel Muir Concurrent 15C GLP1 and SGLT-2 and Hypertension Grand Ballroom 6 Moderators: Alexander Staruschenko, PhD, FAHA and Jan Michael Williams, PhD 10:30 AM Invited Lecture: SGLT2 Inhibitors and GLP-1 Receptor Agonists at the Intersection of Kidney and Cardiovascular Disease Daniel Edmonston, MD, MHS 070 11:00 AM Right Heart, Right Drug: Sodium-Glucose Co-Transporter 2 Inhibitors in Pulmonary Hypertension: Reduced Mortality and Heart Failure Outcomes In a Large Propensity-Matched Cohort Rayan Salih 071 11:15 AM Comparative Antihypertensive Effects of Emerging Cardiorenal Therapies in Chronic Kidney Disease: A Network Meta-Analysis of SGLT2 Inhibitors, MRAs, and GLP-1 Receptor Agonists Jayashree Ravikumar 072 11:30 AM Cardiovascular Outcomes in Hypertensive Adults Treated with GLP-1 Receptor Agonists: A Retrospective Cohort Study Shaival Sharma 073 11:45 AM A Systems-Level Intervention Improved Alignment of Initial Hypertension Pharmacotherapy with Clinical Practice Guidelines at a Veterans Affairs Medical Center Matthew Escalona
12:30 pm to 1:00 pm	Sponsored Learning Studio Corcept Therapeutics Grand Ballroom 7-10 (Includes Lunch) Cracking the Code: Uncover a Hidden Driver of Resistant Hypertension Join us as leading experts uncover the role of hypercortisolism as a hidden driver of resistant hypertension and share their clinical insights to help identify this often-overlooked contributor. Presented by: Jan N. Basile, MD, FACP, FAHA, FASH; Medical University of South Carolina Kevin M. Pantalone, DO, ECNU, FACE; Cleveland Clinic Raymond R. Townsend, MD, FAHA, FASH; University of Pennsylvania
1:00 pm to 1:30 pm	Sponsored Learning Studio Mineralys Therapeutics Laurel A-D (Includes Lunch) A Case of Treatment Resistant Hypertension: The Role of Dysregulated Aldosterone Review the spectrum of dysregulated aldosterone in hypertension, including Primary Aldosteronism which often presents today as treatment-resistant hypertension Review aldosterone synthase inhibition (ASI) for the treatment of uncontrolled hypertension, including treatment-resistant hypertension Present the Launch-HTN phase 3 global trial and response to treatment with lorundrostat, an aldosterone synthase inhibitor Presented by Jan N. Basile, MD, FACP, FAHA, FASH, Professor of Medicine
12:00 pm to 1:30 pm	Or Lunch on Your Own
1:30 pm to 3:00 pm	Session 16 Concurrent Sessions A and B Invited Lectures followed by Oral Abstract Presentations Concurrent C (Primary Care) Concurrent 16A Genetics, Proteomics, and Metabolomics Grand Ballroom 1-5 Moderators: R. Ariel Gomez, MD, FAHA, and Mingyu Liang, MB, PhD 1:30 PM Invited Lecture: PRDM6 and Hypertension Arya Mani, MD 074 2:00 PM Uncovering Hundreds of New Loci from a Multi-Ancestry Study of Blood Pressure Traits in Over 2.5M Individuals Hannah McKenzie Seagle 075 2:15 PM Blood pressure polygenic score predicts long-term blood pressure control and treatment-resistant hypertension So Mi Jemma Cho 076 2:30 PM Chronic AT1 Receptor Blockade Restores Cardiac Mitochondrial Redox and Calcium-Handling Proteomic Profiles in (mRen2)27 Hypertensive Rats Berwin Singh Swami Vetha 077 2:45 PM Semaglutide Attenuates High-Fat Diet-Induced Hypertension in Dahl Salt-Sensitive Rats Adam Lauver Concurrent 16B Cardio-Renal Disease Grand Ballroom 7-10 Moderators: Jordana Cohen, MD, MSCE and Johannes Stegbauer, MD 1:30 PM Invited Lecture: Circulating Extracellular Vesicles in the Pathogenesis of Heart Failure in Patients 3 with Chronic Kidney Disease Susmita Sahoo, PHD 078 2:00 PM Rho Kinase: Key Mediator of Diastolic Dysfunction in Chronic Kidney Disease Walia Zahra 079 2:15 PM Eplerenone treatment limit electrocardiogram alteration in a non-diabetic chronic kidney disease rat model Matthieu SOULIE 080 2:30 PM Loss of Cardiac Piezo1 Channels and Endothelial Cell Microvascular Rarefaction Contribute to the Development of Hypertension-Induced Heart Failure with Mildly Reduced Ejection Fraction in Male BPH/2J Mice Laena Pernomian 081 2:45 PM Mortality Trends in Isolated Systolic, Diastolic, and Combined Hypertension: Insights from the NHANES Database Abdelrahman Abdalla Concurrent 16C: Hypertension Across the Lifespan (Primary Care track sessions) Grand Ballroom 6 Moderators: Amy Kogon, MD, MPH and Mingyu Zhang, PhD, MHS, FAHA 1:30 The Importance of Early Life Exposures on Later Cardiovascular Health Kartikeya Makker, MD, MPH 1:50 Unique Challenges in the Treatment of Hypertension in Children and Adolescence Meghan McLaughlin, MD 2:10 Young Adults: How to Transition from Pediatric Care Smoothly Andrew M. South, MD, MS 2:30 Treatment of Older Adults to Protect Brain Health Lewis Lipsitz, MD 2:50 - 3:00 Discussion and Q&A
3:00 pm to 3:30 pm	Break
3:30 pm to 5:30 pm	Session 17 Council on Hypertension Mid-Career Award for Research Excellence Council on Kidney in Cardiovascular Disease Mid-Career Achievement Award Grand Ballroom 1-5 Moderators: Steven Crowley and Uta Erdbrügger, MD 3:30 PM The Endothelium Unmasked: New Insights into Dysfunction and Disease Gaetano Santulli, MD, PHD, FAHA 4:00 PM The Emerging Role of Polyamine Metabolism in the Kidney Daria Ilatovskaya, MS, PhD, FAHA Concurrent Sessions A and B Oral Abstract Sessions (following the lectures) Concurrent Session C (Primary Care) 4:30 – 5:30 Primary Care track sessions Concurrent Sessions 17C1 and 17C2 Concurrent17 A Mitochondria and Hypertension Grand Ballroom 1-5 Moderators: Daria Ilatovskaya, MS, PhD, FAHA and TBD 082 4:30 PM Cardiac-Specific Reduction of Serum Response Factor Ameliorates Mitochondrial Dysfunction and Cardiac Hypertrophy in Aging Hearts Pankaj Patyal 083 4:45 PM Mitochondrial acetylation of endothelial LCAD and SOD2 promotes female endothelial dysfunction and hypertension Anna Dikalova 084 5:00 PM Progressive Mitochondrial Dysfunction in Proximal Tubules Triggers Cortical Bioenergetic Failure in Kidneys During Salt-Sensitive Hypertension Sri Rahavi Boovarahan 085 5:15 PM Plant-based Diets Linked to Lowering of BP Differentially Remodels Gut Microbiota and Metabolites in Dahl SS/MCW Rats and Humans Justine M Abais-Battad Concurrent 17B Renal Hemodynamics and Chronic Kidney Disease Grand Ballroom 7-10 Moderators: Nirupama Ramkumar MD MPH and Jing (Jason) Wu, PhD, FAHA 086 4:30 PM Exposure to Per- and Polyfluoroalkyl Substances Induces Salt-Sensitive Hypertension via Epithelial Sodium Channel – The First Experimental Evidence Supporting Causality Jing Liu 087 4:45 PM Oxidative Stress Impairs Fatty Acid Oxidation and Induces Proteolysis in Dahl Salt-Sensitive Rats Satoshi Shimada 088 5:00 PM Ultrafast Doppler Ultrasound as a Noninvasive Proxy for Renal Vascular Function in a Mouse Model of Hypertension Benjamin Wall 089 5:15 PM Increased Susceptibility to Hypertension and Renal Damage After Ureter Obstruction Reversal in Hypoplastic Kidneys Samaneh Goorani 3:30 – 5:30 Concurrent 17C Primary Care Track Sessions 3:30 – 4:30 PM 17C1 Beyond The Office, Seated BP: How to Interpret Atypical BP Data Grand Ballroom 6 Moderators: Stephen P. Juraschek, MD, PhD and Yuan Ma, MBBS, PhD 3:30 Blood Pressure Sitting, Standing or Supine: What Does it all Mean? John M. Giacona, PhD, PA-C 3:45 In a World Where Everyone Measures Blood Pressure, Making Sense of the Noise Carissa M Baker-Smith, MD MPH MS 4:00 Novel Community Blood Pressure Screening Environments: From Car to Kiosks Junichi Ishigami, MD, MPH 4:15 Blood Pressure on the Go: Impact of Non-Rest on Blood Pressure Bethany Barone Gibbs, PhD 4:30 – 5:30 PM 17C2 Rethinking the Box: When Using Less Traditional Blood Pressure Reduction Strategies Delivers More Grand Ballroom 6 Moderators: Jan Basile, MD, FAHA and Angela L. Price, MD 4:30 How to Implement Stress Reduction in Blood Pressure Management: Pharmacological and Non-Pharmacological Intervention Anika L. Hines, PhD, MPH, Med 4:45 Identity Re-Boot SGLT2/GLP1RAs as Blood Pressure Drugs Catherine G. Derington, PharmD, MS 5:00 Role of Salt Substitutes and Diet Modification in the Management of Hypertension: Can We SaSS It Up? Matti Marklund, PhD, MSE 5:15 Emerging Therapeutics for Treatment of Hypertension: New Oral and Parenteral Options Prof Markus Schlaich
5:45 pm to 6:15 pm	Session 18 Excellence Award for Hypertension Research Lectures Grand Ballroom 1-5 Moderators: Curt D. Sigmund, PhD, FAHA and R. Ariel Gomez, MD, FAHA 5:45 PM Molecular Mechanisms of Preeclampsia S. Ananth Karumanchi, MBBS 6:05 PM Discovery for Tomorrow's Medicine: Taking Responsibility for Planetary Health Dominik N. Müller, PhD
7:00 pm to 10:00 pm	Hypertension Council Gala Dinner (Ticketed event offsite) (Need to purchase a ticket?) McCormick & Schmick’s Seafood and Steaks 711 Eastern Ave, Baltimore, MD 21202 Includes the presentation of the following Awards: Fernando Elijovich Early Career Clinician Scientist Award Catherine G. Derington, PharmD, MS Irvine Page -Alva Bradley Lifetime Achievement Award Kailash N. Pandey, PhD, FAHA Excellence Award for Hypertension Research S. Ananth Karumanchi, MBBS Dominik N. Müller, PhD

About This Meeting

Hypertension 2025 Scientific Sessions is considered the premier scientific meeting on the subject in the world. A collaborative effort between the Council on Hypertension and the Council on the Kidney in Cardiovascular Disease, the science submitted to this conference continues to bring us the most up to date developments on our understanding of: the causes of hypertension; its relationship to stroke, cardiac disease and kidney dysfunction; and the most effective means for detecting, evaluating and treating high blood pressure across diverse populations.

This year's programming also includes:

Recent Advances sessions and lectures on cutting-edge science, followed by oral abstract presentations
Clinical Science/Clinical Practice track
Primary Care track
Oral abstract sessions highlighting Early Career oral abstract presentations
Networking sessions
Trainee Advocacy Committee (TAC) Poster session and competition
Award Lecture sessions

Learning Objectives

Discuss recent advances and emerging experimental models in hypertension and kidney disease.
Summarize findings from recent clinical trials and the impact on future treatment and/or management of hypertensive and kidney-related disorders.
Describe new therapeutic options and technologies for patients with hypertension and kidney disease.
Describe the most up-to-date clinical guideline recommendations for the prevention, diagnosis, and management of hypertension and kidney disease.